专利检索 ap:("ISIS PHARMACEUTICALS, INC.") AND inv:"ACKERMANN, Elizabeth, A." 第 1 页

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发明公开
ANTISENSE MODULATION OF CELLULAR INHIBITOR OF APOPTOSIS-1 EXPRESSION 审中-公开
标题翻译：蜂窝电话的反义调节抑制剂细胞凋亡表达

公开(公告)号：EP1163373A1

公开(公告)日：2001-12-19

申请号：EP99928729.5

申请日：1999-06-16

申请人： ISIS PHARMACEUTICALS, INC.

发明人： BENNETT, C., Frank , ACKERMANN, Elizabeth, A. , COWSERT, Lex, M.

IPC分类号： C12Q1/68 , C07H21/04 , C12N15/00

CPC分类号： C12N15/113 , A61K38/00 , C12N2310/315 , C12N2310/316 , C12N2310/318 , C12N2310/3181 , C12N2310/321 , C12N2310/334 , C12N2310/341 , C12N2310/346 , Y02P20/582 , C12N2310/3525 , C12N2310/3521

摘要： Antisense compounds, compositions and methods are provided for modulating the expression of Cellular Inhibitor of Apoptosis-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Cellular Inhibitor of Apoptosis-1. Methods of using these compounds for modulation of Cellular Inhibitor of Apoptosis-1 expression and for treatment of diseases associated with expression of Cellular Inhibitor of Apoptosis-1 are provided.