公开(公告)号：EP2462240A1

公开(公告)日：2012-06-13

申请号：EP10807057.4

申请日：2010-08-03

申请人： Institute For Hepatitis And Virus Research

发明人： ROMANO, Patrick, Robert ,  MEHTA, Anand ,  BLOCK, Timothy, M.

IPC分类号： C12Q1/00 ,  G01N33/569 ,  C07K1/00

CPC分类号： G01N33/57438 ,  G01N33/6893 ,  G01N2333/4724 ,  G01N2440/38 ,  G01N2800/085 ,  G01N2800/50

摘要： The present invention provides methods, compositions, apparatus, and kits for assessing glycoforms of proteins as a biomarker for disease. A purified recombinant form of lectin is used as a detector molecule to specifically label target sugars expressed in disease states. The high affinity of recombinant lectin allows for automation of assays that would be used in the diagnosis of diseases such as, but not limited to, cancer or liver disease.

公开(公告)号：EP2462240B1

公开(公告)日：2017-07-05

申请号：EP10807057.4

申请日：2010-08-03

申请人： Institute For Hepatitis And Virus Research

发明人： ROMANO, Patrick, Robert ,  MEHTA, Anand ,  BLOCK, Timothy, M.

IPC分类号： C07K14/47 ,  G01N33/574 ,  G01N33/68

CPC分类号： G01N33/57438 ,  G01N33/6893 ,  G01N2333/4724 ,  G01N2440/38 ,  G01N2800/085 ,  G01N2800/50