专利检索 ap:("Isis Pharmaceuticals, Inc.") AND inv:"MACLEOD, Robert A." 第 1 页

1.

发明公开
MODULATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 (STAT3) EXPRESSION 审中-公开
标题翻译：转录3的信号转换器和活化剂调制（STAT3）的表达

公开(公告)号：EP2697243A2

公开(公告)日：2014-02-19

申请号：EP12763390.7

申请日：2012-03-30

申请人： Isis Pharmaceuticals, Inc.

发明人： SWAYZE, Eric E. , FREIER, Susan M. , MACLEOD, Robert A. , KIM, Youngsoo

IPC分类号： C07H21/04 , C12N15/11

CPC分类号： C12N15/113 , C07H21/00 , C07H21/04 , C12N15/00 , C12N15/11 , C12N15/1135 , C12N2310/11 , C12N2310/315 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12N2320/30 , C12N2310/321 , C12N2310/3521 , C12N2310/3525

摘要： Disclosed herein are antisense compounds and methods for decreasing STAT3 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate hyperproliferative diseases.