公开(公告)号：EP2844064B1

公开(公告)日：2018-09-05

申请号：EP13730330.1

申请日：2013-05-02

申请人： Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta ,  Avantea S.r.l.

发明人： CASALONE, Cristina ,  GALLI, Cesare ,  CHIEPPA, Maria Novella ,  CORONA, Cristiano ,  BENDOTTI, Caterina ,  PEROTA, Andrea ,  LAZZARI, Giovanna ,  CARAMELLI, Maria ,  LAGUTINA, Irina

IPC分类号： A01K67/027 ,  C12N9/02 ,  C12N15/877 ,  C12N15/85 ,  C12N9/00

CPC分类号： A01K67/0275 ,  A01K2217/052 ,  A01K2227/108 ,  A01K2267/0318 ,  C12N9/0089 ,  C12N15/8509 ,  C12N15/8778 ,  C12N2800/30 ,  C12N2830/46

摘要： Transgenic swine suitable to develop Amyotrophic Lateral Sclerosis, being transgenic for expressing an exogenous gene in neuronal cells, wherein the exogenous gene is a human SOD1 gene carrying a mutation.