公开(公告)号：EP2380901A4

公开(公告)日：2012-12-26

申请号：EP09838334

申请日：2009-02-06

申请人： KIKKOMAN CORP

发明人： TAKEHARU NAKAHARA ,  RIICHIRO UCHIDA ,  HITOMI AOTA ,  KATSUTOSHI SUGIMOTO ,  TAKUYA SATO

IPC分类号： C07K5/083

CPC分类号： C07K2/00 ,  A61K38/00 ,  C07K5/06078 ,  C07K5/06113 ,  C07K5/06165 ,  C07K5/06173 ,  C07K5/0806 ,  C07K5/0808 ,  C07K5/0819

摘要： To provide ACE inhibitory peptides which can effectively inhibit ACE by a small amount of ingestion and have no fear of causing side effects and which can be orally ingested easily during daily life by persons having high blood pressure, and compositions comprising the peptides. The peptides represented by the following structural formulae (1) to (9), and salts thereof are provided. (1) Asp-Arg-Pro, (2) Asn-Trp, (3) Val-Gly-Leu, (4) Ile-Gly-Val, (5) Gly-Val-Pro, (6) Ile-Pro-Tyr, (7) pyroGlu-Pro, (8) Tyr-Thr, (9) Pra-Trp