利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

3 条记录 (耗时 0.009 秒)

    Carbamic acid derivatives and method for preparing the same
    2.
    发明公开
    Carbamic acid derivatives and method for preparing the same 失效
    Carbaminsäurederivate和Verfahren zu ihrer Herstellung。

    公开(公告)号：EP0497303A2

    公开(公告)日：1992-08-05

    申请号：EP92101449.4

    申请日：1992-01-29

    申请人： KYORIN PHARMACEUTICAL CO., LTD.

    发明人： Takano, Yasuo ,  Takadoi, Masanori ,  Hirayama, Takashi ,  Yamanishi, Atsuhiro

    IPC分类号： C07D401/04 ,  C07D417/04 ,  C07D401/14 ,  C07D211/40 ,  C07D211/54 ,  C07D211/46 ,  A61K31/445

    CPC分类号： C07D401/04 ,  C07D211/60 ,  C07D401/14 ,  C07D417/04

    摘要： Anti-dementia medicaments comprising a carbamic acid derivatives or their pharmaceutically acceptable acid addition salts having an anti-amnesic activity as an active ingredient are provided. The carbamic acid derivatives are represented by a general formula (1)

    wherein Ar denotes an aromatic heterocyclic ring which may have at least one substituent or its benzene-condensed ring, or phenyl group which may have at least one substituent, R¹ denotes hydrogen atom or lower alkyl group, R² denotes lower alkyl group which may be substituted with halogen atom, phenyl group which may have at least one substituent, naphthyl group, or five- or six-membered heterocyclic ring and its benzene-condensed ring, X and Y, which may be the same or different, denote sulfur atom or oxygen atom.

    摘要翻译： 提供了包含具有抗遗忘活性作为活性成分的氨基甲酸衍生物或其药学上可接受的酸加成盐的抗痴呆药物。 氨基甲酸衍生物由通式（1）表示，其中Ar表示可具有至少一个取代基的芳族杂环或其苯稠合的环，或可具有至少一个取代基的苯基， 1表示氢原子或低级烷基，R 2表示可以被卤素原子取代的低级烷基，可具有至少一个取代基的苯基，萘基或五元或六元杂环， 苯稠合环，X和Y可以相同或不同，表示硫原子或氧原子。