公开(公告)号：EP4198512A1

公开(公告)日：2023-06-21

申请号：EP21856250.2

申请日：2021-08-12

申请人： Korea Institute of Science and Technology ,  Korea University Research and Business Foundation

发明人： RYU, Ju Hee ,  KWON, Ick Chan ,  KIM, Kwangmeyung ,  KIM, Han Young ,  KIM, Eun-sun

IPC分类号： G01N33/68 ,  G01N33/58 ,  C12Q1/25 ,  A61K47/64 ,  A61P35/00

摘要： The present disclosure relates to a cancer cell-specific complex for targeting cancer. The complex for targeting cancer according to the present disclosure includes EGF, but is affected more by lysosomal activity rather than the EGFR signaling pathway, and thus can overcome the shortcomings of the existing EGF therapy-based diagnostic and therapeutic compositions and provide successfully personalized and improved effects of treating, preventing and alleviating cancer.
A diagnostic composition according to the present disclosure enables the prediction of the anticancer performance of a therapeutic composition of the present disclosure in a subject, and thus enables anticancer treatment to be designed stably.