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公开(公告)号：EP1777215A1
公开(公告)日：2007-04-25
申请号：EP05768520.8
申请日：2005-08-03
IPC分类号： C07C227/16 , C07C229/56
CPC分类号： C07C227/16 , C07C229/56
摘要： A method for producing 2-amino-5-iodobenzoic acid which comprises bringing 2-aminobenzoic acid (A) and molecular iodine (B) into reaction with each other in the liquid phase in the presence of an oxidizing agent. Hydrogen peroxide is preferable as the oxidizing agent. This method does not require a step for purifying 2-amino-5-iodobenzoic acid or a step for recovering iodine, and 2-amino-5-iodobenzoic acid having excellent quality can be produced economically advantageously with a great yield. The product can be advantageously used as an intermediate for drugs, an agricultural chemical and a raw material for functional chemicals.
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公开(公告)号：EP1777215B1
公开(公告)日：2010-11-03
申请号：EP05768520.8
申请日：2005-08-03
IPC分类号： C07C227/16 , C07C229/56
CPC分类号： C07C227/16 , C07C229/56
摘要： Disclosed is a method for producing 2-amino-5-iodobenzoic acid wherein 2-aminobenzoic acid (A) and a molecular iodine (B) are reacted in a liquid phase in the presence of an oxidant. Hydrogen peroxide is preferably used as the oxidant. This method does not require a step for refining 2-amino-5-iodobenzoic acid or a step for recovering iodine, and enables to economically advantageously produce high-quality 2-amino-5-iodobenzoic acid with high yield. The thus-produced 2-amino-5-iodobenzoic acid can be advantageously used as a pharmaceutical intermediate, an agricultural chemical, a raw material for functional chemicals or the like.
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