专利检索 ap:("Medichem S.A.") AND inv:"MOLINS I GRAU, Elies" 第 1 页

1.

发明公开
SYNTHESES AND PREPARATIONS OF POLYMORPHS OF CRYSTALLINE ARIPIPRAZOLE 审中-公开
标题翻译：合成及晶型从结晶阿立哌唑筹备工作

公开(公告)号：EP1879865A1

公开(公告)日：2008-01-23

申请号：EP06795321.6

申请日：2006-04-13

申请人： Medichem S.A.

发明人： BENITO VELEZ, Monica , MOLINS I GRAU, Elies , ARNALOT AGUILAR, Carmen , MANGION, Bernardino

IPC分类号： C07D215/22 , A61K31/496 , A61P25/18

CPC分类号： C07D215/22

摘要： The invention relates to polymorphic crystalline forms of aripiprazole, synthetic processes for their preparation and pharmaceutical compositions containing the same. These crystalline forms of aripiprazole can be readily milled and can be easily combined with various pharmaceutical adjuvants without effecting changes to their crystalline structure when, for example, pressed into tablet or capsule form.

2.

发明公开
NEW PROCESS FOR THE PREPARATION OF A LEUKOTRIENE ANTAGONIST 审中-公开
标题翻译：新方法用于生产EINESLEUKOTRIENANTAGONISTEN

公开(公告)号：EP1817289A1

公开(公告)日：2007-08-15

申请号：EP04798127.9

申请日：2004-11-30

申请人： Medichem, S.A.

发明人： CHAMORRO GUTIERREZ, Iolanda , BOSCH I LLADO, Jordi , MOLINS I GRAU, Elies

IPC分类号： C07D215/18

CPC分类号： C07D215/18

摘要： The present invention relates to a novel process for the preparation of montelukast sodium, a compound of Formula (1b) and precursors thereof. The invention further concerns the free acid of this compound in crystalline form, obtainable for the first time by the new process.