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公开(公告)号:EP1276769A1
公开(公告)日:2003-01-22
申请号:EP01934903.4
申请日:2001-04-25
申请人: Merck & Co., Inc.
发明人: LIU, Qingyun , LYNCH, Kevin, R. , HOWARD, Andrew, D. , MELLIN, Theodore, N. , STRACK, Alison , VAN DER PLOEG, Leonardus, H., T. , WANG, Ruiping , JIANG, Qingping , WILLIAMS, David
CPC分类号: C07K14/70571 , C07K14/72 , C07K2319/00 , G01N33/6893 , G01N33/74 , G01N2500/00
摘要: A new neuromedin U receptor, designated NMUR2 has been found, which is involved in modulation of feeding behavior in mammals. Ligands of this receptor are able to modulate eating, and weight gain. Amino acid sequences of the human and rat forms, as well as their nucleic acid sequences are given.