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公开(公告)号:EP2120584A1
公开(公告)日:2009-11-25
申请号:EP07853393.2
申请日:2007-12-14
申请人: Merck & Co., Inc.
IPC分类号: A01N55/00 , A61K31/695
CPC分类号: C07F7/0812
摘要: Compounds of formula I: I wherein at least one of R4 and R5 comprises Si(R6)3 as a substituent selectively attenuate production of Aß(1-42) and hence find use in treatment of Alzheimer's disease and related conditions.