公开(公告)号：EP2344118B1

公开(公告)日：2018-02-21

申请号：EP09748691.4

申请日：2009-10-30

申请人： Natura Cosméticos S.a.

发明人： DA LUZ MOREIRA, Patrícia ,  ARROTEIA, Kelen Fabiola ,  FERRARI, Cintia Rosa ,  SIQUEIRA JORGE, AdrianoTadeu ,  CARVALHÃES LAGO, Juliana ,  GESZTESI, Jean Luc

IPC分类号： A61K8/67 ,  A61K8/97 ,  A61Q19/08

CPC分类号： A61Q19/08 ,  A61K8/678 ,  A61K8/97 ,  A61K2800/522

摘要： The present application describes an antioxidant complex having a synergistic effect between its ingredients. Said mixture comprises: a) vitamin E and/or derivatives thereof; b) green tea extract and/or derivatives thereof; and c) cacao extract. Examples of cosmetic and pharmaceutical compositions comprising said antioxidant complex and a physiologically acceptable carrier are also described. The antioxidant complex of the present invention, as well as the aforementioned compositions, aid in preventing and protecting against cell and skin damages resulting from the action of free radicals, and also provide DNA, protein and cell membrane protection.

公开(公告)号：EP3932387A1

公开(公告)日：2022-01-05

申请号：EP21179563.8

申请日：2013-10-01

申请人： Natura Cosméticos S.A.

发明人： FERRARI, Cintia Rosa ,  ZIMBARDI, Daniela ,  PLACONÁ DINIZ, Gabriela ,  DE ASSIS SANTOS, Ícaro ,  LORENCINI, Marcio ,  DA LUZ MOREIRA, Patrícia

IPC分类号： A61K8/9794 ,  A61K36/889 ,  A61Q19/00 ,  A61Q17/00 ,  A61P17/16 ,  A61P43/00 ,  A61Q19/08 ,  A61K8/92

摘要： The present invention is directed to cosmetic and/or pharmaceutical compositions comprising at least one plant lipid, having as its main application the treatment of keratinous materials, particularly skin, hair, scalp, nails and eyelashes, by modulating the expression of genes responsible for ROS metabolism, lipid metabolism, skin integrity, cell renewal, cell differentiation, strengthening the skin barrier, calcium metabolism, cell proliferation, tissue healing and/or repair, cell adhesion, carbohydrate metabolism, hydration, skin homeostasis/maintenance, skin defense and/or protection, remodeling and/or extracellular matrix synthesis, skin peeling, tissue maintenance, cell signaling, normal development of the epidermis, epidermal barrier function, development of the skin, dermis-epidermis junction, antiinflammatory or antioxidant action in keratinous materials, through the modulation of the expression of the genes involved in said functions. The present invention also teaches methods of modulating the expression of genes responsible for such functions of keratinous materials and the use of said plant lipids in the preparation of said compositions.

公开(公告)号：EP2344118A1

公开(公告)日：2011-07-20

申请号：EP09748691.4

申请日：2009-10-30

申请人： Natura Cosméticos S.a.

发明人： DA LUZ MOREIRA, Patrícia ,  ARROTEIA, Kelen Fabiola ,  FERRARI, Cintia Rosa ,  SIQUEIRA JORGE, AdrianoTadeu ,  CARVALHÃES LAGO, Juliana ,  GESZTESI, Jean Luc

IPC分类号： A61K8/67 ,  A61K8/97 ,  A61Q19/08

CPC分类号： A61Q19/08 ,  A61K8/678 ,  A61K8/97 ,  A61K2800/522

摘要： The present application describes an antioxidant complex having a synergistic effect between its ingredients. Said mixture comprises: a) vitamin E and/or derivatives thereof; b) green tea extract and/or derivatives thereof; and c) cacao extract. Examples of cosmetic and pharmaceutical compositions comprising said antioxidant complex and a physiologically acceptable carrier are also described. The antioxidant complex of the present invention, as well as the aforementioned compositions, aid in preventing and protecting against cell and skin damages resulting from the action of free radicals, and also provide DNA, protein and cell membrane protection.

公开(公告)号：EP2903590A2

公开(公告)日：2015-08-12

申请号：EP13786146.4

申请日：2013-10-01

申请人： Natura Cosméticos S.A.

发明人： FERRARI, Cintia Rosa ,  ZIMBARDI, Daniela ,  PLACONÁ DINIZ, Gabriela ,  DE ASSIS SANTOS, Ícaro ,  LORENCINI, Marcio ,  DA LUZ MOREIRA, Patrícia

IPC分类号： A61K8/97

CPC分类号： A61K8/922 ,  A61K2800/75 ,  A61Q17/00 ,  A61Q19/08

摘要： The present invention is directed to cosmetic and/or pharmaceutical compositions comprising at least one plant lipid, having as its main application the treatment of keratinous materials, particularly skin, hair, scalp, nails and eyelashes, by modulating the expression of genes responsible for ROS metabolism, lipid metabolism, skin integrity, cell renewal, cell differentiation, strengthening the skin barrier, calcium metabolism, cell proliferation, tissue healing and/or repair, cell adhesion, carbohydrate metabolism, hydration, skin homeostasis/maintenance, skin defense and/or protection, remodeling and/or extracellular matrix synthesis, skin peeling, tissue maintenance, cell signaling, normal development of the epidermis, epidermal barrier function, development of the skin, dermis-epidermis junction, anti-inflammatory or antioxidant action in keratinous materials, through the modulation of the expression of the genes involved in said functions. The present invention also teaches methods of modulating the expression of genes responsible for such functions of keratinous materials and the use of said plant lipids in the preparation of said compositions.

摘要翻译： 本发明涉及化妆品和/或药物组合物包含至少一种植物脂质，具有角质材料，尤其是皮肤，头发，头皮，指甲和睫毛的治疗作为其主要应用，通过调节负责ROS的基因的表达 代谢，脂质代谢，皮肤完整性，细胞更新，细胞分化，加强皮肤屏障，钙代谢，细胞增殖，组织愈合和/或修复的细胞，粘附，碳水化合物代谢，水合，皮肤稳态/维护，皮肤防御和/或 保护，重塑和/或细胞外基质的合成，皮肤剥离，组织维护，细胞信号传导，表皮的正常发育，表皮屏障功能，皮肤的发展，真皮 - 表皮交界处，在角蛋白材料的抗炎或抗氧化作用，通过 在根据所述函数所涉及的基因的表达的调节。 因此，本发明教导了调制负责角质材料的搜索功能和使用时，所述的计划脂质所说的组合物的制备中的基因的表达的方法。