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1.发明公开MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS 审中-公开Monosaccharidderivate alsEntzündungshemmendeund / oder Anti-Tumor Agentien
公开(公告)号：EP1842855A2
公开(公告)日：2007-10-10
申请号：EP07105121.3
申请日：2007-03-28
发明人： Sattigeri, Viswajanani Jitendra , Arora, Sudershan K. , Salman, Mohammad , Palle, Venkata P. , Mukherji, Ashis , Verma, Ashwani Kumar , Malhotra, Sanjay , Dharmarahan, Sankaranarayanan , Ray, Abhijit , Shirumalla, Raj Kumar
IPC分类号： C07H9/04 , C07H15/00 , C07H3/02 , A61K31/70 , A61K31/7004 , A61K31/7028 , A61K31/7042 , A61P37/00 , A61P35/00 , A61P17/00 , A61P11/06
摘要： The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, Ulcerative colitis, acne, atherosclerosis, cancer, pruritis and allergic rhinitis. Pharmacological compositions containing compounds disclosed herein and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, psoriasis, allograft rejection, inflammatory bowel disease, Ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.
摘要翻译： 本发明涉及作为抗炎剂的单糖衍生物。 本文中的化合物障碍可用于抑制和预防炎症和相关病理，包括炎症和自身免疫性疾病，例如支气管哮喘，类风湿性关节炎，I型糖尿病，多发性硬化，同种异体移植排斥，牛皮癣，炎性肠病，溃疡性结肠炎，痤疮， 动脉粥样硬化，癌症，瘙痒症和过敏性鼻炎。 包含本文公开的化合物的药理学组合物和治疗支气管哮喘，慢性阻塞性肺病，类风湿性关节炎，多发性硬化，1型糖尿病，牛皮癣，同种异体移植排斥，炎性肠病，溃疡性结肠炎，痤疮，动脉粥样硬化，癌症，瘙痒，过敏性 还提供了使用这些化合物的鼻炎和其它炎性和/或自身免疫性疾病。
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2.发明公开
公开(公告)号：EP1842855A3
公开(公告)日：2007-12-05
申请号：EP07105121.3
申请日：2007-03-28
发明人： Sattigeri, Viswajanani Jitendra , Arora, Sudershan K. , Salman, Mohammad , Palle, Venkata P. , Mukherji, Ashis , Verma, Ashwani Kumar , Malhotra, Sanjay , Dharmarahan, Sankaranarayanan , Ray, Abhijit , Shirumalla, Raj Kumar
IPC分类号： C07H9/04 , C07H15/00 , C07H3/02 , A61K31/70 , A61K31/7004 , A61K31/7028 , A61K31/7042 , A61P37/00 , A61P35/00 , A61P17/00 , A61P11/06
摘要： The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, Ulcerative colitis, acne, atherosclerosis, cancer, pruritis and allergic rhinitis. Pharmacological compositions containing compounds disclosed herein and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, psoriasis, allograft rejection, inflammatory bowel disease, Ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.
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