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公开(公告)号：EP1968945A2
公开(公告)日：2008-09-17
申请号：EP06842663.4
申请日：2006-12-21
发明人： KUMAR, Naresh , KAUR, Jaskiran , PALLE, Venkata P. , BHATT, Beenu , JINDAL, Shelly , CHUGH, Anita , GUPTA, Suman , RAY, Abhijit , MALHOTRA, Shivani , SHIRUMALLA, Raj Kumar
IPC分类号： C07D233/14 , C07D233/60 , C07D233/61 , C07D401/12 , A61K31/4164 , A61K31/4439 , A61P1/00 , A61P11/00 , A61P13/00
CPC分类号： C07D233/54 , C07D233/14 , C07D233/56 , C07D233/64 , C07D401/12
摘要： Compounds of Formula (I), wherein represents a single bond when G is -OH and double bond when G is -O; R1 and R2 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, heterocyclylalkyl or heteroarylalkyl; R3 is selected from the group selected from hydrogen, hydroxy, alkoxy, alkenyloxy or alkynyloxy; X is selected from oxygen, -NH, -NR (wherein R is alkyl, alkenyl, alkenyl, alkynyl or aryl), sulphur or no atom; Het is heterocyclyl or heteroaryl; n is an integer from 1 to 6; are muscarinic receptor antagonists, which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and 4 i gastrointestinal systems mediated through muscarinic receptors.
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2.发明公开DERIVATIVES OF MONOSACCHARIDES FOR THE TREATMENT OF COPD AND ALLERGIC RHINITIS 审中-公开单糖用于治疗COPD和过敏性鼻炎衍生物
公开(公告)号：EP1915160A2
公开(公告)日：2008-04-30
申请号：EP06780155.5
申请日：2006-07-20
发明人： RAY, Abhijit , SHIRUMALLA, Raj Kumar , MOOKHTIAR, Kasim , SATTIGERI, Viswajanani J. , PALLE, Venkata P. , SALMAN, Mohammad
CPC分类号： A61K31/70
摘要： The present invention relates to the use of derivatives of monosaccharides as 5-lipoxygenase inhibitor.
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3.发明公开DERIVATIVES OF PENTOSE MONOSACCHARIDES AS ANTI-INFLAMMATORY COMPOUNDS 审中-公开PENTOSEMONOSACCHARIDEN作为抗炎化合物衍生物
公开(公告)号：EP1902063A2
公开(公告)日：2008-03-26
申请号：EP05850707.0
申请日：2005-12-22
发明人： SATTIGERI, Jitendra, Viswajanani , ARORA, Sudershan, K. , SALMAN, Mohammad , PALLE, Venkata, P. , NAGARAJAN, Muthukaman , SHIRUMALLA, Raj Kumar , AULAKH, Gurpreet Kaur , RAY, Abhijit
IPC分类号： C07H15/02
摘要： The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds of this invention can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and autoimmune diseases, for example, bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection or psoriasis. The present invention also relates to pharmacological compositions containing these monosaccharide derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, and other inflammatory and/or auto immune disorders.
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