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1.发明授权3-(GUANIDINOCARBONYL)HETEROCYCLE DERIVATIVES, PREPARATION PROCESS AND INTERMEDIATES OF THIS PROCESS, THEIR USE AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM 有权3-（GUANIDINOCARBONYL）HETEROCYCLUSDERIVATIVE，HERSETLLUNGSVERFAHREN和用于该方法的中间产物，其使用AS药品和药物组合物含
公开(公告)号：EP1641791B1
公开(公告)日：2009-07-29
申请号：EP04739421.8
申请日：2004-05-28
发明人： CARRY, Jean-Christophe , DOERFLINGER, Gilles, 2 avenue du Berry , GENEVOIS-BORELLA, Arielle , EVERS, Michel , LE BRUN, Alain , MARTIN, Jean-Paul , DESMAZEAU, Pascal , MIGNANI, Serge , KLEEMANN, Heinz-Werner
IPC分类号： C07D471/04 , A61K31/437
CPC分类号： C07D471/04
摘要： The present invention relates to the novel compounds of the formula (I) and their pharmaceutically acceptable salts. The inventive compounds are suitable, for example, as antiarrhythmic medicaments with a cardioprotective component for infarction prophylaxis and infarction treatment and for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiologicaI processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure.
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2.发明公开3-(GUANIDINOCARBONYL)HETEROCYCLE DERIVATIVES, PREPARATION PROCESS AND INTERMEDIATES OF THIS PROCESS, THEIR USE AS MEDICAMENTS, AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM 有权3-（GUANIDINOCARBONYL）HETEROCYCLUSDERIVATIVE，HERSETLLUNGSVERFAHREN和用于该方法的中间产物，其使用AS药品和药物组合物含
公开(公告)号：EP1641791A1
公开(公告)日：2006-04-05
申请号：EP04739421.8
申请日：2004-05-28
发明人： CARRY, Jean-Christophe , DOERFLINGER, Gilles, 2 avenue du Berry , GENEVOIS-BORELLA, Arielle , EVERS, Michel , LE BRUN, Alain , MARTIN, Jean-Paul , DESMAZEAU, Pascal , MIGNANI, Serge , KLEEMANN, Heinz-Werner
IPC分类号： C07D471/04 , A61K31/437
CPC分类号： C07D471/04
摘要： The present invention relates to the novel compounds of the formula (I) and their pharmaceutically acceptable salts. The inventive compounds are suitable, for example, as antiarrhythmic medicaments with a cardioprotective component for infarction prophylaxis and infarction treatment and for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiologicaI processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure.
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