-
1.发明授权Delivery device for zero-order release of an active principle into a dissolution fluid and process for its preparation 失效用于将有效原理零点释放到溶解流体中的输送装置及其制备方法
公开(公告)号：EP0169821B1
公开(公告)日：1991-02-06
申请号：EP85830182.3
申请日：1985-07-16
发明人： Colombo, Paolo , Conte, Ubaldo , Reiner, Alberto
IPC分类号： A61K9/22
CPC分类号： A61K9/209 , Y10S514/965
-
2.发明公开Delivery device for zero-order release of an active principle into a dissolution fluid and process for its preparation 失效为在非溶剂液体中的活性成分的零级释放递送装置，以及它们的制备方法。
公开(公告)号：EP0169821A2
公开(公告)日：1986-01-29
申请号：EP85830182.3
申请日：1985-07-16
发明人： Colombo, Paolo , Conte, Ubaldo , Reiner, Alberto
IPC分类号： A61K9/22
CPC分类号： A61K9/209 , Y10S514/965
摘要： A delivery device for zero-order release of an active principle into a dissolution fluid includes a reservoir consisting of a solid matrix of a homogeneous mixture of a polymer material, at least a portion of the active principle and an additive soluble in the dissolution fluid with negative heat of solution, a coating on the solid matrix-type reservoir of a first, release rate-controlling insoluble membrane which modulates the active principle release according to the desired kinetics; and a second, protective membrane on the release rate-controlling membrane of a soluble polymer material.
-
3.发明公开Delivery device for zero-order release of an active principle into a dissolution fluid and process for its preparation 失效用于将有效原理零点释放到溶解流体中的输送装置及其制备方法
公开(公告)号：EP0169821A3
公开(公告)日：1987-05-06
申请号：EP85830182
申请日：1985-07-16
发明人： Colombo, Paolo , Conte, Ubaldo , Reiner, Alberto
IPC分类号： A61K09/22
CPC分类号： A61K9/209 , Y10S514/965
摘要： A delivery device for zero-order release of an active principle into a dissolution fluid includes a reservoir consisting of a solid matrix of a homogeneous mixture of a polymer material, at least a portion of the active principle and an additive soluble in the dissolution fluid with negative heat of solution, a coating on the solid matrix-type reservoir of a first, release rate-controlling insoluble membrane which modulates the active principle release according to the desired kinetics; and a second, protective membrane on the release rate-controlling membrane of a soluble polymer material.
-
-
搜索结果
3 条记录 (耗时 0.01 秒)
