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公开(公告)号：EP2307485A1
公开(公告)日：2011-04-13
申请号：EP09777112.5
申请日：2009-07-10
发明人： DIRIX, Yvo , BRUNNER, Lorenz , SANDER, Jonathan
IPC分类号： C08J3/00
CPC分类号： C08J5/00 , A61L27/16 , A61L27/505 , C08K5/1545 , C08K9/10 , C08L23/06 , C08L2207/068
摘要： A method for obtaining a composition of at least two components, comprising the steps of: providing at least one first fluid component; providing at least one second solid component and processing it so that the first component can diffuse into the second component; and diffusing the first component into the second component. A composition prepared by such a method.
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公开(公告)号：EP2291417B1
公开(公告)日：2013-09-25
申请号：EP08758493.4
申请日：2008-05-13
发明人： BRUNNER, Lorenz , DIRIX, Yvo , SCHMOTZER, Hans
CPC分类号： C08K5/005 , C08J5/10 , C08L23/06 , C08L2666/02
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3.发明公开PROCESSES COMPRISING CROSSLINKING POLYETHYLENE OR USING CROSSLINKED POLYETHYLENE 审中-公开聚乙烯联网或使用交联聚乙烯全面的过程
公开(公告)号：EP2083981A1
公开(公告)日：2009-08-05
申请号：EP06818318.5
申请日：2006-10-30
发明人： SCHMOTZER, Hans , DIRIX, Yvo , SMITH, Paul , TERVOORT, Theo , BRUNNER, Lorenz
IPC分类号： B29C43/00
CPC分类号： B29C43/003 , B29C43/006 , B29K2023/0683 , B29L2031/7532
摘要： The current invention discloses a process comprising compacting a composition comprising virgin ultrahigh molecular weight polyethylene (UHMW PE), said UHMW PE having a weight average molecular weight of at least 1,000,000 g/mol, to provide a compacted composition comprising virgin UHMW PE, sintering said compacted composition, and crosslinking said UHMW PE.
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公开(公告)号：EP2307485B1
公开(公告)日：2016-09-28
申请号：EP09777112.5
申请日：2009-07-10
发明人： DIRIX, Yvo , BRUNNER, Lorenz , SANDER, Jonathan
IPC分类号： C08J3/00
CPC分类号： C08J5/00 , A61L27/16 , A61L27/505 , C08K5/1545 , C08K9/10 , C08L23/06 , C08L2207/068
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公开(公告)号：EP2197503A2
公开(公告)日：2010-06-23
申请号：EP08799161.8
申请日：2008-09-04
发明人： BRUNNER, Lorenz , DIRIX, Yvo , SCHMOTZER, Hans , JANI, Shilesh C.
CPC分类号： A61L27/26 , A61L27/50 , A61L27/54 , A61L2300/428
摘要： A prosthetic device may comprise an insert having a first surface configured to contact a first prosthetic component and a bearing surface configured to articulate against a second prosthetic component. The insert comprises an ultra-high molecular weight polyethylene and vitamin E. The vitamin E may have a concentration in the range of.02 to.12 wt% first mixed with the ultra-high molecular weight polyethylene and then molded with the ultra-high molecular weight polyethylene at a temperature greater than the melting point of the ultra-high molecular weight polyethylene. The ultra-high molecular weight polyethylene and vitamin E may be gamma irradiated with a dosage of radiation between 5 and 20 Mrad. The insert may be machined prior to gamma irradiating the insert in air such that the gamma irradiation, at suitably high dosages, may also sterilize the insert.
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公开(公告)号：EP2125907A1
公开(公告)日：2009-12-02
申请号：EP07723439.1
申请日：2007-03-20
发明人： BRUNNER, Lorenz , DIRIX, Yvo , SCHMOTZER, Hans
CPC分类号： C08J7/123 , C08F8/00 , C08F2810/20 , C08J3/203 , C08J3/28 , C08J2323/06 , C08K5/005 , C08L23/06 , C08F110/02
摘要： The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron bean irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.
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公开(公告)号：EP2398515A1
公开(公告)日：2011-12-28
申请号：EP09789470.3
申请日：2009-02-19
发明人： BRUNNER, Lorenz , DIRIX, Yvo , JANI, Shilesh , TOMMASINI, Roberto
CPC分类号： A61L27/54 , A61L27/16 , A61L2300/102 , A61L2300/404 , A61L2300/408 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/624 , A61L2300/63 , C08L23/06
摘要： A substance, which contains anti-inflammatory substances, anti-microbial substances, anti-tumor substances, anti-viral substances, and/or bone stimulating substances, as an additive, can be added to an UHMWPE material for the production of a medical implant for imparting benign body response properties to the medical implant.
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公开(公告)号：EP2398515B1
公开(公告)日：2018-09-05
申请号：EP09789470.3
申请日：2009-02-19
发明人： BRUNNER, Lorenz , DIRIX, Yvo , JANI, Shilesh , TOMMASINI, Roberto
CPC分类号： A61L27/54 , A61L27/16 , A61L2300/102 , A61L2300/404 , A61L2300/408 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/624 , A61L2300/63 , C08L23/06
摘要： A substance, which contains anti-inflammatory substances, anti-microbial substances, anti-tumor substances, anti-viral substances, and/or bone stimulating substances, as an additive, can be added to an UHMWPE material for the production of a medical implant for imparting benign body response properties to the medical implant.
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公开(公告)号：EP2125907B1
公开(公告)日：2012-11-21
申请号：EP07723439.1
申请日：2007-03-20
发明人： BRUNNER, Lorenz , DIRIX, Yvo , SCHMOTZER, Hans
CPC分类号： C08J7/123 , C08F8/00 , C08F2810/20 , C08J3/203 , C08J3/28 , C08J2323/06 , C08K5/005 , C08L23/06 , C08F110/02
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公开(公告)号：EP2291417A1
公开(公告)日：2011-03-09
申请号：EP08758493.4
申请日：2008-05-13
发明人： BRUNNER, Lorenz , DIRIX, Yvo , SCHMOTZER, Hans
CPC分类号： C08K5/005 , C08J5/10 , C08L23/06 , C08L2666/02
摘要： The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron bean irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants.
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