公开(公告)号：EP3450439A1

公开(公告)日：2019-03-06

申请号：EP17789327.8

申请日：2017-04-17

申请人： Sumitomo Chemical Co., Ltd.

发明人： SATO, Kanako ,  IHARA, Hideki

IPC分类号： C07F9/572

摘要： A compound represented by formula (3):

or an enantiomer thereof, which is a monomer that can be used for the production of a single-stranded nucleic acid molecule capable of suppressing the expression of a target gene, can be obtained by:
reacting a compound represented by formula (1):

or an enantiomer thereof with 6-hydroxyhexanoic acid in a solvent in the presence of an additive such as 1-hydroxybenzotriazole and a condensing agent, and then mixing the resultant reaction mixture, water, and a base such as alkali metal hydroxide to produce a compound represented by formula (2) :

or an enantiomer thereof; and
reacting the compound represented by formula (2) or an enantiomer thereof with 2-cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite in a solvent in the presence of a coupling activator such as a diisopropylaminetetrazole salt.

公开(公告)号：EP2813492A1

公开(公告)日：2014-12-17

申请号：EP13746367.5

申请日：2013-02-05

申请人： Sumitomo Chemical Co., Ltd

发明人： OHSHITA, Jun ,  AWANO, Tomotsugu ,  IHARA, Hideki

IPC分类号： C07D307/14 ,  A01N43/08 ,  A01N43/16 ,  A01P7/04 ,  C07D309/04

CPC分类号： A01N43/40 ,  A01N43/08 ,  A01N43/16 ,  C07D307/14 ,  C07D307/16 ,  C07D309/04 ,  C07D309/06 ,  C07D405/12

摘要： An amide compound represented by formula (I) has an excellent pest control effect. (In the formula, Y represents a 3-7 membered saturated heterocyclic ring which contains, as ring-forming component(s), one or more atoms or groups that are selected from the group consisting of an oxygen atom and -S(O) t -, the saturated heterocyclic ring may have one to three atoms or groups selected from group D and t represents 0 or the like; X represents a C 1 -C 8 chain hydrocarbon group having one group that is selected from group A; W represents -CR 8 - or the like; r represents 1 or the like; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 may be the same or different and each represents a hydrogen atom or the like; and n represents 1 or the like.)

摘要翻译： 由式（I）表示的酰胺化合物具有优异的害虫防治效果。 （在该式中，Y表示3-7元饱和杂环，其含有作为成环组分的一个或多个选自氧原子和-S（O）的一个或多个原子或基团， t - ，饱和杂环可以具有1至3个选自D组的原子或基团，t表示0等; X表示具有一个选自A组的C 1 -C 8链烃基; W表示 -CR 8 - 等; r表示1等; R 1，R 2，R 3，R 4，R 5，R 6，R 7和R 8可以相同或不同，各自表示氢原子 等等; n表示1等。）