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公开(公告)号:EP2516452A1
公开(公告)日:2012-10-31
申请号:EP10796407.4
申请日:2010-12-22
申请人: TEAGASC, The Agriculture and Food Development Authority , University College Cork, National University Of Irland Cork
发明人: HILL, Colin , COTTER, Paul , ROSS, Paul, R. , FIELD, Desmond
IPC分类号: C07K14/315 , A61K38/16
CPC分类号: C07K14/315 , A61K38/00
摘要: A Nisin derivative or variant, comprising an amino acid substitution at amino acid position 29 in the amino acid sequence. The Nisin derivative exhibits enhanced antimicrobial activity when compared to wild type Nisin. The Nisin derivative has an application as a natural food additive and as a therapeutic agent.