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公开(公告)号：EP0291605B1
公开(公告)日：1993-03-31
申请号：EP87309644.0
申请日：1987-10-30
IPC分类号： A61K43/00
CPC分类号： A61K51/0489 , A61K2121/00
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公开(公告)号：EP0291605A3
公开(公告)日：1989-07-26
申请号：EP87309644.0
申请日：1987-10-30
IPC分类号： A61K43/00
CPC分类号： A61K51/0489 , A61K2121/00
摘要： Bone marrow is suppressed by administering at least one bone marrow suppressing radionuclide composition having at least one of Samarium-153, Gadolinium-159, or Holmium-166 and at least one of ethylenediaminetetramethylenephosphonic acid, diethylenetriaminepentamethylenephosphonic acid, hydroxyethylethylenediaminetrimethylenephosphonic acid, nitrilotrimethylenephosphonic acid or tris(2-aminoethyl)aminehexamethylenephosphonic acid, or a physiologically-acceptable salt thereof.
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公开(公告)号：EP0291605A2
公开(公告)日：1988-11-23
申请号：EP87309644.0
申请日：1987-10-30
IPC分类号： A61K43/00
CPC分类号： A61K51/0489 , A61K2121/00
摘要： Bone marrow is suppressed by administering at least one bone marrow suppressing radionuclide composition having at least one of Samarium-153, Gadolinium-159, or Holmium-166 and at least one of ethylenediaminetetramethylenephosphonic acid, diethylenetriaminepentamethylenephosphonic acid, hydroxyethylethylenediaminetrimethylenephosphonic acid, nitrilotrimethylenephosphonic acid or tris(2-aminoethyl)aminehexamethylenephosphonic acid, or a physiologically-acceptable salt thereof.
摘要翻译： 通过施用至少一种骨髓抑制放射性核素组合物抑制骨髓，所述组合物具有至少一种钐-153，钆-159或钬-166以及至少一种乙二胺四亚甲基膦酸，二亚乙基三胺五亚甲基膦酸，羟乙基乙二胺三亚甲基膦酸，次氮基三亚甲基膦酸或三 2-氨基乙基）胺六亚甲基膦酸或其生理上可接受的盐。
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公开(公告)号：EP0271180B1
公开(公告)日：1993-05-26
申请号：EP87307266.4
申请日：1987-08-17
发明人： Tomalia, Donald A. , Kaplan, Donald A. , Kruper, William J. , Cheng, Roberta C. , Tomlinson, Ian A. , Fazio, Michael J. , Wilson, Larry R. , Hedstrand, David M.
CPC分类号： B82Y5/00 , A01N25/10 , A61K47/59 , A61K47/595 , A61K47/6885 , A61K47/6949 , C08G73/02 , C08G83/003 , C08L101/005
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公开(公告)号：EP0271180A1
公开(公告)日：1988-06-15
申请号：EP87307266.4
申请日：1987-08-17
发明人： Tomalia, Donald A. , Kaplan, Donald A. , Kruper, William J. , Cheng, Roberta C. , Tomlinson, Ian A. , Fazio, Michael J. , Wilson, Larry R. , Hedstrand, David M.
CPC分类号： B82Y5/00 , A01N25/10 , A61K47/59 , A61K47/595 , A61K47/6885 , A61K47/6949 , C08G73/02 , C08G83/003 , C08L101/005
摘要： Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricutural, pharmaceutical, or other material have been prepared. These conjugates have particularly advantageous properties due to the unique characteristics of the dendrimer.
摘要翻译： 已经制备了由至少一种树枝状大分子与携带的农业，药物或其它材料的至少一个单元结合的星状共轭体。 由于树枝状聚合物的独特特征，这些共轭物具有特别有利的性质。
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公开(公告)号：EP0271180B2
公开(公告)日：1997-06-18
申请号：EP87307266.4
申请日：1987-08-17
发明人： Tomalia, Donald A. , Kaplan, Donald A. , Kruper, William J. , Cheng, Roberta C. , Tomlinson, Ian A. , Fazio, Michael J. , Wilson, Larry R. , Hedstrand, David M.
CPC分类号： B82Y5/00 , A01N25/10 , A61K47/59 , A61K47/595 , A61K47/6885 , A61K47/6949 , C08G73/02 , C08G83/003 , C08L101/005
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