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公开(公告)号:EP0039920A3
公开(公告)日:1982-01-27
申请号:EP81103498
申请日:1981-05-07
IPC分类号: C07D487/04 , C07D471/14 , C07D495/14 , C07D491/14 , C07D241/44 , A61K31/495 , C07D471/04 , C07D249/00 , C07D241/00 , C07D221/00 , C07D333/00 , C07D307/00
CPC分类号: C07D471/04 , C07D241/44 , C07D471/14 , C07D487/04
摘要: Anti-allergic compounds of the formulae
wherein,
X is S or O; R 1 and R 2 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl, sulfonamido, halogen, alkoxy, alkenyloxy, alkynyloxy, cyano, hydroxy, acyloxy, nitro, amino, alkylamino, alkanoylamino, carbalkoxyamino, methanesulfonyl, carboxy, carbalkoxy, trihalomethyl, or taken together, methylenedioxy; R 3 and R 4 is hydrogen, alkyl, alkenyl, alkynyl, aryl, acyl, aralkyl, cycloalkyl, cycloalkyl CH 2 -, or carbalkoxy; and Z forms a heterocyclic ring with the two carbon atoms to which it is attached;and intermediates for their preparation.摘要翻译: 下式的抗过敏化合物其中X是S或O; 烷基,链烯基,炔基,环烷基,芳基,芳烷基,亚磺酰氨基,卤素,烷氧基,烯氧基,炔氧基,氰基,羟基,酰氧基,硝基,氨基,烷基氨基,烷酰基氨基, 三卤代甲基,或者合在一起,亚甲二氧基; R3和R4是氢,烷基,链烯基,炔基,芳基,酰基,芳烷基,环烷基,环烷基CH2-或烷氧羰基; Z与其所连接的两个碳原子形成杂环;以及用于其制备的中间体。
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公开(公告)号:EP0039920A2
公开(公告)日:1981-11-18
申请号:EP81103498.2
申请日:1981-05-07
IPC分类号: C07D487/04 , C07D471/14 , A61K31/495
CPC分类号: C07D471/04 , C07D241/44 , C07D471/14 , C07D487/04
摘要: Anti-allergic compounds of the formulae
wherein,
X is S or O;
R 1 and R 2 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl, sulfonamido, halogen, alkoxy, alkenyloxy, alkynyloxy, cyano, hydroxy, acyloxy, nitro, amino, alkylamino, alkanoylamino, carbalkoxyamino, methanesulfonyl, carboxy, carbalkoxy, trihalomethyl, or taken together, methylenedioxy;
R 3 and R 4 is hydrogen, alkyl, alkenyl, alkynyl, aryl, acyl, aralkyl, cycloalkyl, cycloalkyl CH 2 -, or carbalkoxy; and
Z forms a heterocyclic ring with the two carbon atoms to which it is attached;and intermediates for their preparation.摘要翻译: 式
的抗过敏化合物,其中X为S或O; R1和R2是氢,烷基,烯基,炔基,环烷基,芳基,芳烷基,亚磺酰氨基,卤素,烷氧基,烯氧基,炔氧基,氰基,羟基,酰氧基,硝基,氨基,烷基氨基,烷酰基氨基,烷氧基氨基,甲磺酰基,羧基, 三卤代甲基,或一起取代亚甲二氧基; R3和R4是氢,烷基,烯基,炔基,芳基,酰基,芳烷基,环烷基,环烷基,环烷基CH2-或碳烷氧基; Z与其所连接的两个碳原子形成杂环; 和中间体的制备。 -
公开(公告)号:EP0039920B1
公开(公告)日:1984-07-25
申请号:EP81103498.2
申请日:1981-05-07
IPC分类号: C07D487/04 , C07D471/14 , A61K31/495
CPC分类号: C07D471/04 , C07D241/44 , C07D471/14 , C07D487/04
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