公开(公告)号：EP2930166A4

公开(公告)日：2016-01-06

申请号：EP12889458

申请日：2012-12-07

申请人： WANHUA CHEMICAL GROUP CO LTD ,  NINGBO WANHUA POLYURETHANES CO

发明人： CHEN CHANGSHENG ,  JIANG JINKE ,  CHEN ZHONGYING ,  CUI JIAOYING ,  WANG JING ,  LI FUGUO ,  LV CHENGGE ,  ZHAO WENJUAN ,  LI YUAN ,  HUA WEIQI

IPC分类号： C07C211/35 ,  C07C209/48 ,  C07C209/52

CPC分类号： C07C253/30 ,  C07C209/48 ,  C07C209/52 ,  C07C2101/14 ,  C07C2601/14 ,  C07C255/46 ,  C07C211/36

摘要： The present invention provides a method for preparing 3-aminomethyl-3,5,5-trimethyl cyclohexylamine. The method comprises: a) reacting 3-cyano-3,5,5-trimethyl cyclohexanone with excess primary amine as well as removing the water generated from the reaction, so that IPN is substantially converted into imine compounds; b) in the presence of an ammonolysis catalyst, mixing the product of step a) with liquid ammonia, making the imine compound perform ammonolysis reaction to generate 3-cyano-3,5,5-trimethyl cyclohexylimine and the primary amine; and c) in the presence of hydrogen and a hydrogenation catalyst, hydrogenating 3-cyano-3,5,5-trimethyl cyclohexylimine obtained in step b) to obtain 3-aminomethyl-3,5,5-trimethyl cyclohexylamine. The method of the present invention avoids the generation of 3,5,5-trimethyl cyclohexanol and 3-aminomethyl-3,5,5-trimethyl cyclohexanol as the major by-products in the prior art, thereby improving the yield of 3-aminomethyl-3,5,5-trimethyl cyclohexylamine.