专利检索 ap:("ZERIA PHARM CO LTD") AND inv:"HIGASHINO R" 第 1 页

1.

发明公开
N-PHENYL-N'-PHENYLPROPYLPIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：（N-苯基-N'-苯基哌嗪）衍生物及其制造方法

公开(公告)号：EP1090913A4

公开(公告)日：2001-11-07

申请号：EP99957637

申请日：1999-06-28

申请人： ZERIA PHARM CO LTD

发明人： SATO HIROKI , NAGANO EIICHI , CHIKAZAWA JUN , TAKEI MINEO , HIGASHINO R

IPC分类号： C07D295/084 , C07D295/092 , C07D209/12 , A61K31/495 , A61P9/00 , C07D295/08

CPC分类号： C07D295/088 , C07D295/092

摘要： N-Phenyl-N'-phenylpropylpiperazine derivatives represented by general formula (1) (wherein R1 is lower alkyl; R2 is lower alkoxy; and R3 is cyano, carboxyl or indolecarbonyl); drugs containing the same; and a process for the preparation thereof. The compounds exhibit potent α¿1?-adrenergic receptor blocking activity and are useful in the prevention and treatment of hypertension, congestive heart failure, myocardial ischemia, arrhythmia, angina pectoris, urinary disturbance and frequent urination due to prostatic hypertrophy, and so on.