公开(公告)号：EP3389780A1

公开(公告)日：2018-10-24

申请号：EP16822441.8

申请日：2016-12-16

申请人： Koninklijke Philips N.V.

发明人： SCHADEWALDT, Nicole ,  PETERS, Jochen

IPC分类号： A61N5/10

CPC分类号： A61N5/1037 ,  A61N5/1038 ,  A61N5/1039

摘要： It is an object of the invention to provide for an improved radiation treatment. According to a first aspect of the invention, this object is achieved by a method for determining a patient specific locally varying margin on a treatment target and/or an organ at risk in order to compensate for local intrafraction motion expected during a radiotherapy fraction to be delivered over a radiotherapy fraction time interval. The patient specific locally varying margin is determined based on a displacement and/or an estimate of the displacement of at least a first location and a second location on the treatment target and/or organ at risk. The method comprises steps of: acquiring a first medical image of the treatment target and/or the organ at risk and acquiring a second medical image of the treatment target and/or the organ at risk, wherein the time between the acquisition of the first medical image and the second medical image is similar to the radiotherapy fraction time interval and determining of positions of the first location and the second location in the first medical image and in the second medical image and using the determined positions for determining the patient specific locally varying margin around the treatment target and/or organ at risk.

公开(公告)号：EP3157411A1

公开(公告)日：2017-04-26

申请号：EP15724274.4

申请日：2015-05-21

申请人： Koninklijke Philips N.V.

发明人： PETERS, Jochen ,  WEESE, Juergen ,  WÄCHTER-STEHLE, Irina

IPC分类号： A61B5/00 ,  A61B5/02

CPC分类号： G06T7/0012 ,  A61B5/0044 ,  A61B5/02028 ,  A61B5/055 ,  A61B6/032 ,  A61B6/503 ,  G06T7/11 ,  G06T2207/10028 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10136 ,  G06T2207/30048 ,  G06T2207/30104

摘要： A system (100) and method are provided for determining an effective cross-sectional area of a tubular cardiovascular structure (400), which may be used in the assessment of blood flow through the tubular cardiovascular structure. Said determining comprises obtaining a three-dimensional Image'of the tubular cardiovascular structure, segmenting the image to obtain a segmentation of the lumen inside the tubular cardiovascular structure, and determining a centerline (430) of the tubular cardiovascular structure. Then, using the segmentation of the lumen, an apparent flow aperture of the tubular cardiovascular structure is determined in the direction of the centerline, e.g., by projecting the segmentation along the direction of the centerline and determining the area in the projection which is free of projected parts. In contrast to area planimetry, the apparent flow aperture does not overestimate the effective cross-sectional area of the tubular cardiovascular structure, and thus may be used to provide a better estimate of the effective cross-sectional area of said cardiovascular structure.

摘要翻译： 提供了用于确定管状心血管结构（400）的有效横截面面积的系统（100）和方法，其可用于评估通过管状心血管结构的血流量。 所述确定包括获得管状心血管结构的三维图像，分割图像以获得管状心血管结构内的腔的分割，并且确定管状心血管结构的中心线（430）。 然后，利用内腔的分割，例如通过沿着中心线的方向投影分割并且确定投影中没有中心线的区域，在中心线的方向上确定管状心血管结构的表观流动孔径 投影部分。 与区域面积测量相比，表观流量孔径不会高估管状心血管结构的有效横截面积，并且因此可用于提供对所述心血管结构的有效横截面积的更好估计。

公开(公告)号：EP3077989A1

公开(公告)日：2016-10-12

申请号：EP14805548.6

申请日：2014-11-26

申请人： Koninklijke Philips N.V.

发明人： GROTH, Alexandra ,  PETERS, Jochen ,  WEESE, Juergen ,  SAALBACH, Axel

IPC分类号： G06T7/00

CPC分类号： G06T7/0012 ,  G06T7/12 ,  G06T7/149 ,  G06T2207/30048

摘要： A system (100) is provided for performing a model-based segmentation of an anatomical structure in a medical image. The system comprises a processor (140) configured for performing a model-based segmentation of the anatomical structure by applying a deformable model to image data (042). Moreover, definition data (220) is provided which defines a geometric relation between a first part and a second part of the deformable model of which a corresponding first part of the anatomical structure is presumed to be better visible in the image data than a corresponding second part of the anatomical structure. The definition data is then used to adjust a fit of the second part of the deformable model. As a result, a better fit of the second part of the deformable model to the second part of the anatomical structure is obtained despite said part being relatively poorly visible in the image data.

摘要翻译： 提供了一种用于执行医学图像中的解剖结构的基于模型的分割的系统（100）。 该系统包括配置用于通过将可变形模型应用于图像数据来执行解剖结构的基于模型的分割的处理器（140）（042）。 此外，提供定义数据（220），其定义可变形模型的第一部分和第二部分之间的几何关系，其中解剖结构的相应的第一部分被假定为在图像数据中比对应的第二部分更好地可见 解剖结构的一部分。 定义数据然后用于调整可变形模型的第二部分的拟合。 结果，尽管所述部分在图像数据中相对较差可见，但获得了可变形模型的第二部分到解剖结构的第二部分的更好拟合。

公开(公告)号：EP3011358A2

公开(公告)日：2016-04-27

申请号：EP14737004.3

申请日：2014-06-19

申请人： Koninklijke Philips N.V. ,  Philips GmbH

发明人： BUERGER, Christian ,  WAECHTER-STEHLE, Irina ,  PETERS, Jochen ,  HANSIS, Eberhard Sebastian ,  WEBER, Frank Michael ,  KLINDER, Tobias ,  RENISCH, Steffen

IPC分类号： G01R33/48 ,  G01R33/56

CPC分类号： G06T7/0014 ,  G01R33/481 ,  G01R33/4828 ,  G01R33/56 ,  G01R33/5608 ,  G06K9/4661 ,  G06K9/52 ,  G06K9/6215 ,  G06K9/6267 ,  G06K2009/4666 ,  G06T7/37 ,  G06T7/60 ,  G06T7/73 ,  G06T11/003 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/20048 ,  G06T2207/30008 ,  G06T2207/30061

摘要： The present invention relates to a method for segmenting MR Dixon image data. A processor and a computer program product are also disclosed for use in connection with the method. The invention finds application in the MR imaging field in general and more specifically may be used in the generation of an attenuation map to correct for attenuation by cortical bone during the reconstruction of PET images. In the method, a surface mesh is adapted to a region of interest by: for each mesh element in the surface mesh: selecting a water target position based on a water image feature response in the MR Dixon water image;selecting a fat target position based on a fat image feature response in the MR Dixon fat image; and displacing each mesh element from its current position to a new position based on both its water target position and its corresponding fat target position.

摘要翻译： 本发明涉及一种用于分割MR Dixon图像数据的方法。 还公开了一种与该方法结合使用的处理器和计算机程序产品。 本发明通常在MR成像领域中应用，并且更具体地可以用于产生衰减图以在PET图像的重建期间校正皮质骨的衰减。 在该方法中，表面网格通过以下方式适应于感兴趣区域：对于表面网格中的每个网格元素：基于MR Dixon水图像中的水图像特征响应来选择水目标位置; 基于MR Dixon脂肪图像中的脂肪图像特征响应来选择脂肪目标位置; 并且基于其水目标位置和其相应的脂肪目标位置，将每个网格元素从其当前位置移位到新位置。