公开(公告)号：EP1054706A1

公开(公告)日：2000-11-29

申请号：EP99903184.2

申请日：1999-01-19

申请人： INTERMEDICS INC.

发明人： PAUL, Patrick, J. ,  PRUTCHI, David

IPC分类号： A61N1/372 ,  G09B23/28

CPC分类号： A61N1/37247 ,  A61N1/37217 ,  G09B23/288

摘要： A training unit (100) generally includes a processor (102), a magnetic field sensor (121), a plurality of control switches (110, 114, 118), and a message and data output device (105). Placing a PEIS magnet (20), constructed in accordance with the ISO/WD 14994 standard, adjacent to or in contact with the training unit activates the magnetic field sensor, a condition detectable by the processor. Activation of the switches determines which of three modes the training unit will operate. In an instructional mode (110), the process provides instructional messages to the operator via the message and data output device, which preferably includes a display (104) and an audio speaker (108). In a coached mode (114), the training unit informs the operator when to place the magnet adjacent to or in contact with the training unit and when to remove the magnet in accordance with the timing intervals of the PEIS entry code. In a practice mode (118), the operator initiates and completes the entry code using a PEIS magnet without coaching. The processor detects the presence of the PEIS magnet, and determines whether the operator correctly performed the entry code. If the operator completes the entry code in either the coached or practice modes, a simulated ECG waveform indicative of a patient's surface ECG upon successful completion of an entry code is shown on the display.

公开(公告)号：EP1052934A1

公开(公告)日：2000-11-22

申请号：EP99906787.9

申请日：1999-02-05

申请人： INTERMEDICS INC.

发明人： PRUTCHI, David

IPC分类号： A61B5/05

CPC分类号： A61B5/4869 ,  A61B5/0456 ,  A61B5/0537

摘要： A cardiorespiratory monitor (100) that generates bioimpedance sensing signals that produce substantially no interference with bioimpedance signals generated by implanted devices. The monitor detects the bioimpedance signal generated by the implanted device, using a voltage detector (128) or a telemetry circuit (104), for example. The monitor has an impedance sensor control circuit (118) to generate a bioimpedance sensing signal that will not interfere with the sensed signal. For instance, if the monitor produces a pulsed sensing signal, the pulses are delivered in an interval of the detected signal where no pulses are present. Similarly, if the monitor produces a high frequency AC sensing signal, the zero crossings of the AC sensing signal are positioned during the delivery of a pulse by the implanted device.

公开(公告)号：EP0799075B1

公开(公告)日：2000-08-23

申请号：EP95943794.8

申请日：1995-12-18

申请人： INTERMEDICS INC.

发明人： SPEHR, Paul, R. ,  FRANKOVICH, Mark, M. ,  WHITE, Mark, A.

IPC分类号： A61N1/05

CPC分类号： A61N1/0573

摘要： An implantable endocardial lead (10) with a retractable helix (48). A specialized stylet (50) can be inserted into the lead (10) at the proximal end and passed through the lead to the distal end. Located at the distal end of the lead is a piston (44) supporting the helix (48). The piston is attached to a coiled trifilar conductor (22) and has an electrode (14) adjacent the helix. Immediately adjacent the piston proximally an additional first short coil of wire is interlocked between the wires of the trifilar conductor (22), providing a female thread within the conductor. The stylet has a second single strand short coil segment spot welded to the stylet adjacent a distal end therof. The stylet (50) is rotated to screw the second short coil segment on the stylet into the first short coil adjacent the piston.

公开(公告)号：EP1021221A1

公开(公告)日：2000-07-26

申请号：EP98939361.6

申请日：1998-08-13

申请人： INTERMEDICS INC.

发明人： SCHROEPPEL, Edward, A.

IPC分类号： A61N1/368

CPC分类号： A61N1/37288 ,  A61N1/3627 ,  A61N1/368

摘要： An implantable medical device (100), such as a pacemaker, for electrically stimulating the heart to beat includes two or more node logic units (310, 320, 330) connected by communication paths (321, 322, 323, 324, 325, 326, 327, 328) over which signals between nodes are conducted. Each node can provide pacing energy to an electrode and amplify electrical signals from the electrode. In response to detecting an electrical event from the electrode or pacing an electrode, each node generates a sense signal or a pace signal. The sense and pace signals form each node can be transmitted to all other nodes with or without a time delay. The time delays between nodes are provided by delay modules (312, 314, 316, 318, 332, 334, 336, 338, 352, 354, 356, 358) controlled by a processor (300). As such, the implantable medical device can be configured to provide a variety of pacemaker therapies.

公开(公告)号：EP1015074A1

公开(公告)日：2000-07-05

申请号：EP98947129.7

申请日：1998-09-16

申请人： INTERMEDICS INC.

发明人： ROUTH, Andre, G.

IPC分类号： A61N1/368 ,  A61N1/05

CPC分类号： A61N1/3622 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/368

摘要： An endocardial apparatus (100) for pacing four chambers of a heart, comprising: a power source (11) housed in an implantable can, first, second and third leads (112, 114, 116) having proximal and distal ends, each lead being electrically connected to the power source at its proximal end and extending into a vein proximal the heart, the first lead (112) connecting at its distal end to an electrode that is in electrical contact with the right atrium of the heart, the second lead (114) connecting at its distal end to an electrode that is in electrical contact with the right ventricle of the heart, the third lead (116) connecting at a point proximal its distal end to a first electrode adjacent means (122, 142, 121, 150) for maintaining the first electrode in electrical contact with the inside of the coronary sinus and oriented so as to stimulate the left atrium of the heart and connecting at its distal end to a second electrode that is in electrical contact with the inside of the great cardiac vein and oriented so as to stimulate the left ventricle of the heart.

公开(公告)号：EP1011789A1

公开(公告)日：2000-06-28

申请号：EP98923682.3

申请日：1998-05-21

申请人： INTERMEDICS INC.

发明人： SCHROEPPEL, Edward, A. ,  SPEHR, Paul, R.

IPC分类号： A61N1/05

CPC分类号： A61N1/056

摘要： A lead assembly (10) includes a proximal end (14) that has a connector (16) for electrical connection to a cardiac stimulator (18), such as a pacemaker, a cardioverter/defibrillator, or a sensing instrument. The lead assembly includes an elongated proximal tubular portion (20) that extends distally from the connector. The distal end of the proximal tubular portion is provided with a branch assembly (22) that is joined distally to two elongated distal lead branches (23a, 23b). The distal branches are provided, respectively, with lead tips (24a, 24b) that each function as electrodes for transferring electrical signals from and/or to the myocardium. The branch assembly includes structure for enabling a surgeon to selectively manipulate the distal branches using a single stylet passed through a single lumen in the proximal tubular portion.

摘要翻译： 引线组件（10）包括具有用于与心脏刺激器（18）电连接的连接器（16）的近端（14），例如起搏器，心律转复器/除颤器或感测器械。 引导组件包括从连接器向远侧延伸的细长的近侧管状部分（20）。 近端管状部分的远端设置有分支组件（22），该分支组件远端地连接到两个细长远端引线分支（23a，23b）。 远端分支分别设有引导尖端（24a，24b），每个引导尖端用作用于从心肌传递电信号和/或传递到心肌的电极。 分支组件包括用于使外科医生能够使用穿过近侧管状部分中的单个内腔的单个探针选择性地操纵远侧分支的结构。

公开(公告)号：EP0994801A1

公开(公告)日：2000-04-26

申请号：EP98931790.4

申请日：1998-07-02

申请人： INTERMEDICS INC.

发明人： JOHNSTON, Matthew, M. ,  CONGER, Steven, R.

IPC分类号： B62K3/02 ,  F16F9/06

CPC分类号： A61N1/056 ,  A61B34/73 ,  A61B2034/733 ,  A61M25/0105 ,  A61M25/0127 ,  A61M25/0158

摘要： Magnetically alterable material, such as magnetostrictive material (28, 54), is used in combination with a suitable substrate (30, 56) and a suitable magnetic field to produce a stylet (20) and lead assembly (10) that curves in response to a suitable magnetic field.

公开(公告)号：EP0975388A1

公开(公告)日：2000-02-02

申请号：EP98915575.9

申请日：1998-04-13

申请人： INTERMEDICS INC.

发明人： ROUTH, Andre ,  BRULS, Annette ,  WOODSON, Drury, III ,  VANDEGRIFF, Joseph ,  VERBOVEN, Yves ,  PAUL, Patrick, J.

IPC分类号： A61N1/368

CPC分类号： A61N1/3622

摘要： An implantable medical device (100) for electrically stimulating the heart to beat including a sense circuit (208, 218) for detecting cardiac electrical activity. The sense circuit includes a sense amplifier (210, 220), band pass filter (215, 225), and threshold detector (227, 240, 245). The threshold detector determines whether sensed cardiac electrical activity resulted from a normal heart beat or an ectopic beat such as a premature ventricular contraction. In a preferred embodiment, latches in the threshold detector are activated by output pulses from a pair of comparators (240, 245). A positive comparator (240) produces an output pulse upon detection of cardiac electrical activity exceeding a positive threshold voltage and a negative comparator (245) produces an output pulse upon detection of cardiac electrical activity more negative than a negative threshold. Threshold logic (250) produces output signals indicative of which comparator first produced an output pulse. A logic and control unit monitors the output signals from the threshold logic and thus determines whether the associated cardiac electrical activity represented a normal heart beat or resulted from an ectopic beat so that appropriate pacing may be provided by the implantable device.

公开(公告)号：EP0968030A1

公开(公告)日：2000-01-05

申请号：EP98913053.9

申请日：1998-03-23

申请人： INTERMEDICS INC.

发明人： PAUL, Patrick, J. ,  PRUTCHI, David

IPC分类号： A61N1/37

CPC分类号： A61N1/3706 ,  A61N2001/083

摘要： A method and apparatus (62) for detecting failure or impending failure of a lead (19) connected to a cardiac stimulator (10) and for providing a warning to a patient or a patient's physician. The impedance of the lead is repeatedly measured (158) and maximum and minimum impedance limits are calculated (160, 164). Repeated impedance measurements are compared with the calculated impedance limits. If the measured impedance falls outside of these impedance limits, an alarm may be given to the patient, or a warning may be given to the patient's physician.

公开(公告)号：EP0942771A1

公开(公告)日：1999-09-22

申请号：EP97946478.0

申请日：1997-10-31

申请人： INTERMEDICS INC.

发明人： STOTTS, Lawrence, J. ,  SCHROEPPEL, Edward, A.

IPC分类号： A61N1

CPC分类号： A61N1/36521

摘要： An implantable, rate responsive pacemaker (10), sensitive to impedance changes (42) in the heart, wherein the cardiac pacing rate and maximum cardiac pacing rate, or either of them, are adjusted as a function of an interval between either the administration of a pacing pulse or the detection of the R-wave and the occurrence of a maximum detected impedance, called the intercept interval. Because an intercept point of the derivative (114) of the impedance curve is detected, the apparatus and method are insensitive to electrode characteristics, electrode movement, body posture or other factors which could affect the magnitude of the detected impedance. The information contained in the intercept interval can also be combined with other sensed or calculated information to set the desired rates.