公开(公告)号：EP1037531A1

公开(公告)日：2000-09-27

申请号：EP98957884.4

申请日：1998-11-12

申请人： BOWLING GREEN STATE UNIVERSITY

发明人： RODGERS, Michael, A., J. ,  JORI, Giulio ,  KENNEY, Malcolm, E.

IPC分类号： A01N43/38

CPC分类号： A61K31/40 ,  A61K41/0057

摘要： The present invention in general terms includes a method of treating cancerous cells containing a pigment, the method including irradiation of the cells with light of comprising the steps: (1) subjecting the cancerous cells to relatively high power light so as to substantially reduce the amount of the pigment in the cells; (2) treating the cancerous cells with one or more photosensitizing agent; followed by (3) subjecting the cancerous cells to relatively low power light so as to activate the photosensitizing agent(s). The figure shows a graph of the rate of tumor growth in mice exposed to irradiation in varying amounts.