公开(公告)号：EP2845854A4

公开(公告)日：2015-03-11

申请号：EP12879240

申请日：2012-08-10

申请人： GUANGZHOU INST BIOMED & HEALTH

发明人： ZHANG YANMEI ,  TALLEY JOHN JEFFREY ,  OBUKOWICZ MARK G ,  TU ZHENGCHAO ,  TORTORELLA MICKY ,  WANG YICAN ,  LIU JIANQI ,  CHEN YAN ,  LIU XIAORONG ,  LU XIN

IPC分类号： C07D311/58 ,  A61K31/352 ,  A61P29/00 ,  A61P35/00

CPC分类号： A61K31/353 ,  A61K31/382 ,  A61K31/47 ,  C07D311/58

摘要： features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.

公开(公告)号：EP2314588A4

公开(公告)日：2012-03-07

申请号：EP09797343

申请日：2009-03-06

申请人： GUANGZHOU INST BIOMED & HEALTH

发明人： DING KE ,  WONG CHIWAI ,  PENG LIJIE ,  KANG ZHANFANG ,  ZHOU XI

IPC分类号： C07D471/04 ,  A61K31/517 ,  A61K31/519 ,  A61P3/00 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/00 ,  A61P9/10

CPC分类号： C07D471/04

公开(公告)号：EP2647700A4

公开(公告)日：2014-09-17

申请号：EP12801798

申请日：2012-03-31

申请人： GUANGZHOU INST BIOMED & HEALTH

发明人： PEI DUANQING ,  WANG TAO

IPC分类号： C12N5/10 ,  C12N5/071

CPC分类号： C12N5/0662 ,  C12N5/0696 ,  C12N2500/38 ,  C12N2501/602 ,  C12N2501/72 ,  C12N2506/13 ,  C12N2510/00