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公开(公告)号：EP1699803A1
公开(公告)日：2006-09-13
申请号：EP04800422.0
申请日：2004-11-30
申请人： AstraZeneca AB
IPC分类号： C07D491/10 , C07D221/20 , C07D209/54 , A61K31/438 , A61K31/403 , A61K31/407 , A61P11/06 , A61P11/08 , A61P19/02 , A61P29/00
CPC分类号： C07D491/10
摘要： The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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公开(公告)号：EP1687311A1
公开(公告)日：2006-08-09
申请号：EP04800321.4
申请日：2004-11-15
申请人： AstraZeneca AB
发明人： BAXTER, Andrew , HOSSAIN, Nafizal , IVANOVA, Svetlana , MENSONIDES-HARSEMA, Marguerite , PIMM, Austen , REUBERSON, James
IPC分类号： C07D491/10 , C07D471/10 , C07D221/20 , C07D209/54 , A61K31/438 , A61K31/403 , A61K31/407 , A61P11/06 , A61P19/02 , A61P29/00
CPC分类号： C07D491/10
摘要： The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译： 本发明提供了式（I）化合物，其中m，R 1，n，R 2，q，X，Y，Z，t，R 3，R 4，R 5，R 6，R 7和R 8如说明书中所定义， ，含有它们的药物组合物及其在治疗中的用途。
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13.发明公开NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY 审中-公开新三环螺衍生物作为趋化因子受体的调节剂
公开(公告)号：EP1678156A1
公开(公告)日：2006-07-12
申请号：EP04775550.9
申请日：2004-10-14
申请人： AstraZeneca AB
发明人： HOSSAIN, Nafizal
IPC分类号： C07D307/94 , A61K31/343 , A61P11/06 , A61P11/08 , A61P19/02 , A61P29/00
CPC分类号： C07D307/94
摘要： The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, R3, R4, R5, R6, R7, R8, t and R9 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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14.发明公开
公开(公告)号：EP1421070A1
公开(公告)日：2004-05-26
申请号：EP02760961.9
申请日：2002-08-21
申请人： AstraZeneca AB
IPC分类号： C07D265/30 , C07D211/20 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12 , A61K31/4523 , A61K31/5377 , A61P11/00 , A61P19/00 , A61P31/00 , A61P37/00
CPC分类号： C07D413/12
摘要： The invention provides compounds of formula (I), in which m, n, X, Y, R?1, R2 and R3¿ are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; and their use in therapy.
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