公开(公告)号：EP3086770A1

公开(公告)日：2016-11-02

申请号：EP13821398.8

申请日：2013-12-27

申请人： Colgate-Palmolive Company ,  Katholieke Universiteit Leuven ,  Universiteit Gent

发明人： STETTLER, Hans ,  TEUGHELS, Wim ,  QUIRYNEN, Marc ,  BOON, Nico

IPC分类号： A61K8/60 ,  A61Q11/00 ,  A61K31/19

摘要： The present invention provides an oral care composition comprising a carboxylic acid of the formula (I) wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and/or re-establishing a healthy oral microflora.

摘要翻译： 本发明提供了包含式（I）的羧酸的口腔护理组合物，其中：R1是H，或是取代或未取代的烷基; R2是H，OH或NH2; 用于：（a）相对于病原性口腔细菌的生长，代谢活性或定殖，在口腔中选择性地促进对口腔健康有益影响的细菌的生长，代谢活动或定植; （b）相对于致病性口腔细菌的生物膜形成，在口腔中选择性地促进对细菌产生对口腔健康具有有益作用的生物膜形成; 或（c）维持和/或重新建立健康的口腔微生物群落。