公开(公告)号：EP1487980A1

公开(公告)日：2004-12-22

申请号：EP03743758.9

申请日：2003-03-12

申请人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION

发明人： WANG, Ming-Bo ,  WATERHOUSE, Peter

IPC分类号： C12N15/11

CPC分类号： C12N15/8249 ,  A01K2217/05 ,  C12N15/111 ,  C12N15/8218 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30

摘要： Methods and means for efficiently downregulating the expression of any gene of interest in eukaryotic cells and organisms are provided. To this end, the invention provides modified antisense and sense RNA molecules, chimeric genes encoding such modified antisense or sense RNA molecules and eukaryotic organisms such as plants, animals or fungi, yeast or molds comprising the modified antisense and/or sense RNA molecules or the encoding chimeric genes.