专利检索 ap:("Five Prime Therapeutics, Inc." OR "Glaxosmithkline Intellectual Property (No. 2) Limited") AND inv:"BELLOVIN, David" 第 2 页

11.

发明公开
CD80 EXTRACELLULAR DOMAIN POLYPEPTIDES AND THEIR USE IN CANCER TREATMENT 审中-公开

公开(公告)号：EP3371208A1

公开(公告)日：2018-09-12

申请号：EP16794878.5

申请日：2016-11-01

申请人： Five Prime Therapeutics, Inc.

发明人： BRENNAN, Thomas , BELLOVIN, David , BUSHA, David , SENNINO, Barbara

IPC分类号： C07K14/705 , A61K38/17

CPC分类号： C07K14/70532 , A61K38/00 , A61K38/1774 , A61K39/39558 , A61K45/06 , C07K16/00 , C07K16/2803 , C07K2317/41 , C07K2319/03 , C07K2319/30

摘要： This application relates to CD80 (B7-1) extracellular domain (ECD) polypeptides and CD80-ECD fusion molecules and their use in treatment of cancer, both alone and in combination with other therapeutic agents, such as immune stimulating agents such as PD-1/PD-L1 inhibitors.