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公开(公告)号：EP2477034B1
公开(公告)日：2019-01-23
申请号：EP10815214.1
申请日：2010-07-15
发明人： SANO Minoru , ONUKI Kazutoshi , SHOJI Yoshiyuki , YAMAZAKI Isao
IPC分类号： G01N35/10
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公开(公告)号：EP3144678A1
公开(公告)日：2017-03-22
申请号：EP15792381.4
申请日：2015-04-22
CPC分类号： G01N35/1009 , G01L19/0092 , G01N1/14 , G01N35/00 , G01N35/00732 , G01N35/025 , G01N35/10 , G01N2035/009 , G01N2035/1018
摘要： The pressure signal process unit 98 acquires data under a predetermined condition. A calculation unit 94 calculates a statistic distance between the acquired data and determination-purpose reference data stored in a storage unit 93. An abnormal dispensing determination unit 97 determines whether or not dispensing is abnormal. A suitability verification unit 95 verifies whether the determination-purpose reference data is suitable for an abnormality detection function to be properly fulfilled. In a case where it is determined that the determination-purpose reference data is not suitable for an abnormality detection function to be properly fulfilled, temporary determination-purpose reference data is prepared so as to be compared with the previously acquired data under a predetermined condition. In a case where a difference therebetween is greater than a predetermined threshold value, the suitability verification unit 95 determines a possibility that an automatic analyzer may have an abnormal component or that a failure may occur in the automatic analyzer, transmits the result to the control instruction unit 99, and causes a display device 92 to display an alarm. In this manner, it is possible to accurately detect a state where component replacement or device adjustment is required, without being affected by a time-dependent change or replacement of each component configuring a channel.
摘要翻译： 压力信号处理单元98在预定条件下获取数据。 计算单元94计算获取的数据与存储在存储单元93中的确定用途参考数据之间的统计距离。异常分配确定单元97确定分配是否异常。 适合性验证单元95验证确定用途参考数据是否适于正确满足异常检测功能。 在确定用于确定用途的参考数据不适于正确满足异常检测功能的情况下，准备临时确定用途参考数据，以便在预定条件下与先前获取的数据进行比较。 在其间的差大于预定阈值的情况下，适用性验证单元95确定自动分析器可能具有异常成分或者在自动分析器中可能发生故障的可能性，将结果发送到控制指令 单元99，并且使显示装置92显示报警。 以这种方式，可以精确地检测需要组件更换或设备调整的状态，而不受时间相关的改变或更换构成通道的每个组件的影响。
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13.发明公开AUTOMATIC ANALYSIS DEVICE AND METHOD FOR DETERMINING MALFUNCTION THEREOF 审中-公开自动分析装置及方法为它厘定MALFUNCTION
公开(公告)号：EP2759835A1
公开(公告)日：2014-07-30
申请号：EP12833461.2
申请日：2012-05-17
CPC分类号： G01F23/00 , G01F23/263 , G01L7/00 , G01N35/1011 , G01N2035/009 , G01N2035/1018 , G01N2035/1025
摘要： An automatic analyzer which performs a suction operation a plurality of times on a same sample has a sample dispensing unit 9, a liquid level sensor which detects the liquid level of the sample in a sample vessel 8, an arithmetic unit 5 which computes a liquid level height h1 at the end of a first suction operation of the two consecutive suction operations from a liquid level height h0 and a sample suction volume V1 detected at the start of the first suction operation, a storage unit 7 which stores the liquid level height h1 computed by the arithmetic unit 5, and a determination unit 18 which compares a liquid level height h2 detected at the start of a second suction operation following the first suction operation with the liquid level height h1 at the end of the first suction operation. The automatic analyzer further determines the presence or absence of a failure in the first or second suction operation according to whether the difference between both liquid level heights h1 and h2 exceeds a threshold value d set in advance. Thus, it is possible to determine whether the suction operation of the sample dispensing unit has been performed properly.
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公开(公告)号：EP3564650A1
公开(公告)日：2019-11-06
申请号：EP17887042.4
申请日：2017-10-24
发明人： ISHIDA Takeshi , YAMAZAKI Isao , ADACHI Sakuichiro , IMAMURA Shin
摘要： An automatic analysis apparatus comprises: a light source that generates light having a center wavelength equal to or shorter than 340 nm; a fluorescent substance that is excited with light of the light source to emit light, and that generates light, together with transmitted light from the light source, having a wavelength of 340 nm to 800 nm; a condenser lens; at least one slit; a reaction cell that holds a reaction solution in which a specimen and a reagent are mixed, and that the light from the light source and the light from the fluorescent substance enter; and a detector that detects light transmitted through the reaction cell. The light source, the fluorescent substance, the condenser lens, and the slit, are provided along a straight light corresponding to the optical axis. The width of an opening of the slit is equal to or narrower than the width of a ray forming an image of the light source at the position of the slit.
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15.发明公开
公开(公告)号：EP3315973A1
公开(公告)日：2018-05-02
申请号：EP16817848.1
申请日：2016-06-27
发明人： HORIE Yosuke , INOUE Tomohiro , NOJIMA Akihiro , MORI Takamichi , YAMAZAKI Isao , ISHIZAWA Masato , TOKIEDA Hitoshi , NONAKA Kouhei
CPC分类号： B08B3/12 , B08B3/14 , G01N1/14 , G01N35/10 , G01N35/1002 , G01N35/1004
摘要： An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a BLT 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.
摘要翻译： 根据本发明的超声波清洁器包括：振动部分222，用于增大清洁槽211中的侧表面侧上的BLT100的超声波振动，通过超声波振动对通过清洁槽211供应到清洁槽211中的清洁液产生气蚀 在喷嘴周围驱动BLT 100而没有不均匀性，并且能够执行有效的喷嘴清洁。
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公开(公告)号：EP3098607A1
公开(公告)日：2016-11-30
申请号：EP15740752.9
申请日：2015-01-13
IPC分类号： G01N35/10
CPC分类号： G01N35/1004 , G01N21/75 , G01N2035/0453
摘要： An automatic analyzer having a washing tank from which water for washing a reagent or sample probe can be drained efficiently and which is capable of further increasing the flow velocity and the flow rate of the water for washing the reagent or sample probe and improving the washing effect is developed. A vent plate 303 is provided in an overflow portion 222 of the washing tank. The washing water from a washing nozzle 201 spreads from a throttle portion 305 and is divided into right and left flows after colliding with the vent plate 303. The washing water flows between the vent plate 303 and the inner wall of the overflow portion 222, and the flows join behind the vent plate 303. After joining, the washing water flows downward along the vent plate 303 and the inner wall of the overflow portion 222 and then is drained. Because a space is created between the washing water which has collided with the vent plate 303 and the washing water joined behind the vent plate 303, the washing water is prevented from completely covering the overflow portion 222, and the airflow can be secured during the drainage.
摘要翻译： 本发明提供一种自动分析装置，该自动分析装置具有清洗槽，能够有效地排出用于清洗试剂或试样探针的水，并且能够进一步提高清洗试剂或试样探针的水的流速和流量，提高清洗效果 被开发。 在清洗槽的溢流部222设有通气板303。 来自清洗喷嘴201的清洗水从节流部305扩散，并在与通气板303碰撞后分成左右流。清洗水在通气板303与溢流部222的内壁之间流动， 流体连接在通气板303后面。接合后，洗涤水沿通气板303和溢流部分222的内壁向下流动，然后排出。 因为在与通气板303碰撞的洗涤水和连接在通气板303后面的洗涤水之间形成空间，所以防止了洗涤水完全覆盖溢流部分222，并且可以在排水期间确保气流 。
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公开(公告)号：EP2755038A1
公开(公告)日：2014-07-16
申请号：EP12829330.5
申请日：2012-07-19
发明人： TAKAHASHI Kenichi , YAMAZAKI Isao
摘要： This invention provides an automatic analyzer adapted to enhance sample/reagent dispensing accuracy, regardless of a difference in sample/reagent dispensing height of a dispensing probe. When the amount of sample in a sample container is small, tip height "h1" of a sample dispensing probe 17 positioned immediately after it has aspirated the sample decreases below tip height "h'" of the sample dispensing probe 17 positioned immediately before it discharges the sample. The sample in this state takes a concave shape at the tip of the sample dispensing probe 17 positioned immediately before it discharges the sample. When the amount of sample in a sample container is large, tip height "h2" of the sample dispensing probe 17 positioned immediately after it has aspirated the sample increases above the tip height "h'" and the sample takes a convex shape at the tip of the sample dispensing probe 17 positioned immediately before it discharges the sample. The difference in the sample-aspirating tip height of the sample dispensing probe 17 appears as a difference in a discharge quantity of the sample. Highly accurate and highly reliable data measurements can be performed by detecting the sample-aspirating tip height of the sample dispensing probe 17 and correcting a discharge quantity of the sample appropriately as the amount of driving of a fixed-volume dispensing syringe 25, according to the detected tip height.
摘要翻译： 本发明提供一种自动分析仪，其适用于提高样品/试剂分配精度，而与分配探针的样品/试剂分配高度的差异无关。 当样本容器中的样本量小时，紧随其后抽出样本的样品分配探针17的尖端高度“h1”低于在其排出之前定位的样品分配探针17的尖端高度“h” 例子。 在该状态下的样品在样品分配探头17的尖端放置样品之前呈凹形。 当样品容器中的样品量大时，位于其吸入样品之后的样品分配探针17的尖端高度“h2”高于尖端高度“h”“，并且样品在尖端处呈凸形 的样品分配探针17位于其放出样品之前。 样品分注探头17的取样尖端高度的差异表现为样品的排出量的差异。 可以通过检测样品分配探针17的取样尖端高度并根据固定容量的分注针筒25的驱动量适当地校正样品的排出量来进行高精度和高可靠性的数据测量。 检测尖端高度。
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公开(公告)号：EP2752667A1
公开(公告)日：2014-07-09
申请号：EP12828882.6
申请日：2012-07-19
IPC分类号： G01N35/00
CPC分类号： G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N2035/1018 , G01N2035/1062 , Y10T436/119163
摘要： An automatic analyzer for judging normal and abnormal of the dispensing operation for detecting abnormal condition of dispensing operation caused by various causes to execute an analysis with high reliability with no requirement of great amount of reference data is realized. A plunger 66 is moved downwardly in predetermined distance while the tip of the sample probe 15 is immersed in a sample to suck the sample into the probe. A pressure sensor 26 detects the pressure fluctuation during the suction operation, an AD converter converting the signals into digital signals to send the signals for a signal processing unit 76. The signal processing unit 76 extracts feature variables data of a suction waveform to calculate the Statistical distance D from normal group data. The Statistical distance D an a threshold value th are compared with each other, it is judged that there is an abnormality in the suction operation when the Statistical distance D is more than or equal to the threshold value th. When the Statistical distance D is smaller than the threshold value th, an operation is proceeded to a discharge operation. After the discharge operation, the values of the feature variables of the discharge waveform are extracted, and the Statistical distance D from the normal group data is calculated. When the Statistical distance d D is more than or equal to the predetermined threshold value th, it is judged that there is an abnormality.
摘要翻译： 实现了一种自动分析器，用于判断分配操作的正常和异常，以检测由各种原因引起的分配操作的异常情况，以高可靠性执行分析，而不需要大量的参考数据。 柱塞66向下移动预定距离，同时将样品探针15的尖端浸入样品中以将样品吸入探针中。 压力传感器26检测抽吸操作期间的压力波动，AD转换器将这些信号转换为数字信号，以将信号发送给信号处理单元76.信号处理单元76提取吸入波形的特征变量数据以计算统计 距正常组数据的距离D. 统计距离D an与阈值th相互比较，当统计距离D大于或等于阈值th时，判断抽吸操作存在异常。 当统计距离D小于阈值th时，操作进行到排出操作。 在放电操作之后，提取放电波形的特征量的值，并且计算与正常组数据的统计距离D. 当统计距离d D大于或等于预定阈值th时，判断存在异常。
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公开(公告)号：EP3581937A1
公开(公告)日：2019-12-18
申请号：EP18751052.4
申请日：2018-01-16
发明人： SHIMADA Masafumi , YAMAZAKI Isao , NISHIDA Masaharu , INOUE Yoko
摘要： The purpose of the present invention is to provide an automatic analysis device capable of determining, through a simple processing, whether or not idle aspirate has occurred. The automatic analysis device according to the present invention determines whether or not idle aspirate has occurred, by calculating a parameter which specifies whether or not the length of a portion of a path through which the sample passes inside a dispensing probe is shorter than that during normal aspirate, the portion being actually filled with a sample
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公开(公告)号：EP3517969A1
公开(公告)日：2019-07-31
申请号：EP17852953.3
申请日：2017-09-14
发明人： YASUI Akihiro , YOSHIDA Gorou , MURAMATSU Yoshiki , YAMAZAKI Isao
摘要： An automatic analyzer (100) includes: a storage unit (21b) that stores various parameters of the automatic analyzer (100) in association with each of elevations used in the automatic analyzers (100), the parameters being optimized for each of the elevations; an input unit (21d) that acquires information of an elevation at which the automatic analyzer (100) is provided; and a controller (21a) that reads the parameters stored in the storage unit (21b) and sets the read parameters to the automatic analyzer (100) based on the elevation acquired by the input unit (21d). As a result, various parameters can be easily adjusted according to a usage environment of the device.
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