公开(公告)号：EP2178848A1

公开(公告)日：2010-04-28

申请号：EP08830598.2

申请日：2008-07-10

申请人： IPSEN PHARMA S.A.S.

发明人： LIBERATORE, Anne-Marie ,  PONS, Dominique ,  BIGG, Dennis ,  PREVOST, Grégoire ,  BREZAK PANNETIER, Marie-Christine

IPC分类号： C07D239/50 ,  C07D405/12 ,  A61K31/506 ,  C07C205/06 ,  C07C225/20 ,  C07C225/22 ,  C07C229/34 ,  C07C229/38 ,  C07C229/42 ,  C07C233/36 ,  C07C255/58

CPC分类号： C07D239/50 ,  C07D213/74 ,  C07D257/04 ,  C07D317/66 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12

摘要： The invention relates to tri-amino-pyrimidine derivatives of the general formula (I) in which Y, R3, W, R4a, R5a, R4b, R5b, n and m are variable. These compounds have a phosphatase CDC25 inhibiting activity and can thus be used as drugs for diseases in which CDC25 are involved. The invention also relates to pharmaceutical compositions containing said products, and to the use thereof for preparing a drug.