公开(公告)号：EP3000824A1

公开(公告)日：2016-03-30

申请号：EP14773035.2

申请日：2014-03-27

申请人： Osaka University

发明人： NAKAGAMI, Hironori ,  MORISHITA, Ryuichi ,  TOMIOKA, Hideki ,  TENMA, Akiko

IPC分类号： C07K7/08 ,  A23L33/17 ,  A61K8/64 ,  A61K38/00 ,  A61P17/00 ,  A61P43/00 ,  A61Q19/08 ,  C07K7/06 ,  C07K5/083 ,  C07K5/11

摘要： An object of the present invention to discover a short peptide having an anti-aging effect and to provide a novel anti-aging agent comprising the peptide as an active ingredient. The inventors have discovered that a peptide consisting of an amino acid sequence ELKLIFLHRLKRLRKRLKRK (SEQ ID NO: 1) or a partial sequence thereof and having one or more effects selected from the group consisting of promoting fibroblast growth, promoting hyaluronic acid production and contracting a collagen gel, or a derivative or salt of the peptide is useful as an active ingredient of an anti-aging agent.

摘要翻译： 本发明的目的是发现具有抗老化作用的短肽并提供包含该肽作为活性成分的新型抗老化剂。 本发明人发现了由氨基酸序列ELKLIFLHRLKRLRKRLKRK（SEQ ID NO：1）或其部分序列组成且具有选自促进成纤维细胞生长，促进透明质酸产生和收缩胶原的一种或多种作用的肽 凝胶或肽的衍生物或盐可用作抗老化剂的活性成分。