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公开(公告)号：EP0484057A3
公开(公告)日：1993-04-21
申请号：EP91309856.2
申请日：1991-10-24
发明人： Walles, Wilhelm E.
IPC分类号： A61L33/00
CPC分类号： A61L33/0011 , A61L33/08 , C08L5/08
摘要： An aqueous paint used to coat a solid substrate to render the surface thereof antithrombogenic comprises an antithrombogenic agent, a non-blood leachable organic polymeric binder and, optionally; a spacer material. Preferably, the aqueous paint contains water, a base, heparin, ethylene acrylic acid copolymer, and colloidal silica. A polymeric resin substrate can be sulfonated prior to coating and/or a coated substrate can be treated with a non-blood leachable bonding agent, especially glutaraldehyde.
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12.发明公开
公开(公告)号：EP0340617A3
公开(公告)日：1991-07-03
申请号：EP89107557.4
申请日：1989-04-26
CPC分类号： C01B17/69 , Y02P20/582
摘要： The present invention provides an apparatus and process for generating a reagent solution of sulfur trioxide in a carrier. The apparatus includes a reagent generator which has associated therewith means for introducing sulfur trioxide from a source into the reagent generator, means for introducing a carrier such as a liquid halocarbon or a gas which is nonreactive with the sulfur trioxide into the reagent generator, and means for introducing oleum into the reagent generator. The sulfur trioxide, carrier and oleum are contacted in the reagent generator to provide a reagent solution of sulfur trioxide in the carrier. Additionally, the apparatus includes means for removing oleum from the reagent generator, as well as means for removing the reagent solution from the reagent generator. In a preferred embodiment, the apparatus for generating the reagent solution also includes, in conjunction with the reagent generator, a treatment chamber for the surface treatment of polymeric resinous material including medical products which have polymeric resinous material on exposed surfaces thereof.
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13.发明公开
公开(公告)号：EP0221591A2
公开(公告)日：1987-05-13
申请号：EP86201731.6
申请日：1986-10-06
发明人： Walles, Wilhelm E.
CPC分类号： C08J7/14
摘要： Plastic containers are treated to provide increased barrier properties to organics and gases such as oxygen by treating the interior surface of the container with SO 3 gas. The SO 3 gas is provided by inserting a solid pellet of poly-SO 3 into the container and evaporating the S0 3 such as with microwave energy. A solid neutralizing agent such as ammonium carbonate is then placed into the container and evaporated with microwave energy to form ammonia which neutralizes the sulfonic acid groups on the surface interior of the container.
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