公开(公告)号：EP2079740B1

公开(公告)日：2012-12-05

申请号：EP07872337.6

申请日：2007-10-31

申请人： Vertex Pharmaceuticals, Inc.

发明人： BENNANI, Yousseff ,  WANG, Tiansheng ,  SALITURO, Francesco ,  DUFFY, John

IPC分类号： C07D471/16 ,  C07D471/22 ,  C07D487/16 ,  A61K31/395 ,  A61K31/435 ,  A61K31/495 ,  A61P11/06 ,  A61P37/06

CPC分类号： C07D471/16 ,  C07D471/22 ,  C07D487/16

公开(公告)号：EP1844050A1

公开(公告)日：2007-10-17

申请号：EP06734381.4

申请日：2006-02-02

申请人： Vertex Pharmaceuticals, Inc.

发明人： LEDEBOER, Mark, W. ,  PIERCE, Albert, C. ,  BEMIS, Guy, W. ,  FARMER, Luc, J. ,  WANG, Tiansheng ,  MESSERSMITH, David ,  DUFFY, John, P. ,  WANG, Jian ,  SALITURO, Francesco, G.

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P7/00 ,  A61P11/00 ,  A61P19/00 ,  A61P37/00

CPC分类号： C07D487/04

摘要： The present invention relates to compounds of formula (I) useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.