公开(公告)号：EP3057578A1

公开(公告)日：2016-08-24

申请号：EP14801919.3

申请日：2014-09-26

申请人： BRIU GmbH

发明人： ROSE, Uwe-Bernd

IPC分类号： A61K9/127 ,  A61P35/00 ,  A61K36/00 ,  A61K9/00 ,  A61K9/107

CPC分类号： A61K9/127 ,  A61K9/0053 ,  A61K9/1075 ,  A61K36/9066

摘要： The invention relates to a composition for the oral administration of curcumin, comprising the following features: (a) the composition is oil-based; (b) it contains curcumin dissolved in the oil; (c) it contains a complex of curcumin and amphiphilic complexing agents; (d) the curcumin content of the composition is at least 3% by weight.

公开(公告)号：EP2996675A1

公开(公告)日：2016-03-23

申请号：EP15714404.9

申请日：2015-02-19

申请人： BRIU GmbH

发明人： ROSE, Uwe-Bernd

IPC分类号： A61K9/00 ,  A61K47/10 ,  A61K47/44 ,  A61K31/00 ,  A61K47/02

CPC分类号： A61K47/44 ,  A61K9/0019 ,  A61K31/122 ,  A61K47/02 ,  A61K47/10

摘要： The invention provides a pharmaceutical formulation which comprises, in accordance with the invention, hypericin or a hypericin derivative in solution in an alcohol, optionally basic salt, especially sodium salt, and a solubilizer. The formulation is anhydrous. The invention provides hypericin stably in solution and enables preparation of an aqueous infusion solution with which hypericin can be administered intravenously in dissolved form. The invention further relates to a process for preparing the pharmaceutical formulation and to an infusion solution comprising the pharmaceutical formulation.