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    Inhaler
    21.
    发明公开
    Inhaler 审中-公开
    吸入器

    公开(公告)号：EP2799102A3

    公开(公告)日：2015-03-11

    申请号：EP14001801.1

    申请日：2010-06-08

    申请人： Ivax Pharmaceuticals Ireland

    发明人： Kaar, Simon G. ,  Walsh, Declan ,  Fenlon, Derek ,  Buck, Dan

    IPC分类号： A61M15/00

    CPC分类号： A61M15/009 ,  A61M15/0026 ,  A61M15/0091 ,  A61M15/0093 ,  A61M15/0096

    摘要： An inhaler (10), such as a breath-actuated metered-dose inhaler, for delivering medicament to a patient. The inhaler (10) comprises a housing for holding the medicament and having an air inlet means (12) and a medicament delivery port which together define an air flow path into which the medicament is dispensed. The air inlet means (12) comprises an array of elongate apertures (24) formed in the housing, the long sides of adjacent apertures (24) facing each other. Each aperture (24) is provided with a respective different opening In an outer surface of the housing. The opening of each aperture (24) extends in two different planes such that, if at least a part of the opening is covered in one of the two different planes during inhalation by the patient, a void space is created between the cover and the aperture (24) so as to provide an air flow path through the void space to the at least one aperture (24).

    摘要翻译： 吸入器（10），例如呼吸驱动的定量吸入器，用于将药物输送给患者。 吸入器（10）包括用于保持药物的壳体并且具有空气入口装置（12）和药物递送端口，空气入口装置（12）和药物递送端口一起限定药物被分配到其中的空气流动路径。 空气入口装置（12）包括形成在壳体中的一组细长孔（24），相邻孔（24）的长边彼此面对。 每个孔（24）在外壳的外表面上设有各自不同的开口。 每个孔（24）的开口在两个不同的平面中延伸，使得如果在患者吸入期间至少一部分开口被覆盖在两个不同平面中的一个中，则在盖和孔之间产生空隙空间 （24），以便提供通过所述空隙空间到所述至少一个孔（24）的气流路径。

    Dose counter for a metered-dose inhaler
    24.
    发明公开
    Dose counter for a metered-dose inhaler 有权
    计量吸入器的剂量计数器

    公开(公告)号：EP2687253A1

    公开(公告)日：2014-01-22

    申请号：EP13004775.6

    申请日：2010-07-28

    申请人： Ivax International B.v.

    发明人： The designation of the inventor has not yet been filed

    IPC分类号： A61M15/00 ,  G06M1/04

    CPC分类号： A61M15/0078 ,  A61M15/0073 ,  A61M15/0075 ,  A61M15/009 ,  A61M2202/064 ,  G06M1/04 ,  G06M1/041 ,  G06M1/24

    摘要： Disclosed herein is a dose counter (18) for counting doses of medicament dispensed by or remaining in a metered-dose inhaler. The dose counter comprises a rotatably mounted first gear wheel (30) having a circular arrangement of ratchet teeth and a display (44) coupled to the first gear wheel, the display having a visible array of dose counting indicia indexable in response to rotary motion of the first gear wheel. The dose counter further comprises an actuator mechanism (20,22,24,26) having a first ratchet drive pawl for engaging the ratchet teeth of the first gear wheel in response to the dispensation of a medicament dose, and a second ratchet drive pawl for engaging the ratchet teeth of a gear wheel coupled to the display. The actuator mechanism is configured such that, in use of the dose counter for counting a dispensed dose, a first ratchet tooth of the first gear wheel is engaged and rotatably driven by the first ratchet drive pawl and then a second ratchet tooth of the gear wheel coupled to the display is engaged and rotatably driven by the second ratchet drive pawl.

    摘要翻译： 本文公开了一种剂量计数器（18），用于对由计量吸入器分配或保留在其中的药剂的剂量进行计数。 剂量计数器包括可旋转地安装的具有棘轮齿的圆形布置的第一齿轮（30）和联接到第一齿轮的显示器（44），显示器具有响应于旋转运动而可索引的剂量计数标记的可见阵列 第一个齿轮。 所述剂量计数器还包括致动器机构（20,22,24,26），所述致动器机构具有第一棘轮驱动棘爪和第二棘轮驱动棘爪，所述第一棘轮驱动棘爪用于响应于药剂剂量的分配而接合所述第一齿轮的所述棘轮齿， 接合连接到显示器的齿轮的棘齿。 致动器机构被构造成使得在使用剂量计数器来计数分配剂量时，第一齿轮的第一棘齿被第一棘轮驱动爪接合并被第一棘轮驱动爪旋转驱动，然后齿轮的第二棘齿 与显示器耦合的第二棘轮驱动棘爪被接合并由第二棘轮驱动棘爪可旋转地驱动。

    Airflow adaptor for a breath-actuated dry powder inhaler
    25.
    发明公开
    Airflow adaptor for a breath-actuated dry powder inhaler 有权
    对于呼吸致动干粉吸入空气电源适配器

    公开(公告)号：EP2596827A2

    公开(公告)日：2013-05-29

    申请号：EP12196742.6

    申请日：2010-11-05

    申请人： NORTON HEALTHCARE LIMITED

    发明人： Blair, Julian Alexander ,  Buck, Daniel ,  Hazenberg, Jan Geert ,  Zeng, Xian-Ming

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0086 ,  A61K9/0075 ,  A61K31/137 ,  A61K31/56 ,  A61M15/0065 ,  A61M15/0091 ,  A61M2202/064 ,  A61M2206/16

    摘要： A deagglomerator for a breath-actuated dry powder inhaler comprising: an airflow adaptor (500); an inner wall (512) defining a swirl chamber (514); a dry powder supply port (522) in the first end (518) of the swirl chamber; at least one inlet port (524,525) in the inner wall of the swirl chamber adjacent to the first end of the swirl chamber providing fluid communication between a region exterior to the deagglomerator and the first end of the swirl chamber; an outlet port providing fluid communication between the second end (520) and the airflow adaptor (501); and wherein the airflow adaptor comprises at least one swirl chamber by-pass port (502,503,504,505) for allowing air to flow from a proximal end of the airflow adaptor to a distal end of the airflow adaptor independently of the swirl-chamber when a breath-induced low pressure is applied to the distal end of the airflow adaptor.

    Dose counters for inhalers and inhalers
    26.
    发明公开
    Dose counters for inhalers and inhalers 有权
    DosiszählwerkefürInhalatoren und Inhalatoren

    公开(公告)号：EP2514467A3

    公开(公告)日：2013-05-01

    申请号：EP11010214.2

    申请日：2011-05-18

    申请人： Ivax Pharmaceuticals Ireland ,  Norton Waterford ,  TEVA Parmaceuticals Ireland

    发明人： Uschold, Robert Charles ,  Karg, Jeffrey A. ,  Clancy, Paul ,  Fenlon, Derek ,  Walsh, Declan ,  Kaar, Simon ,  Hazenberg, Jan Geert ,  Buck, Dan

    IPC分类号： A61M15/00 ,  G06M1/24

    CPC分类号： A61M15/0078 ,  A61M11/00 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0065 ,  A61M15/007 ,  A61M15/0071 ,  A61M15/009 ,  A61M2202/064 ,  A61M2205/6063 ,  A61M2207/00 ,  A61M2207/10 ,  G06M1/246 ,  Y10T29/49 ,  Y10T29/49764 ,  Y10T29/49826

    摘要： A manually operated measured dose inhaler (12) includes a dose counter chamber (66) including a dose display tape (112) driven by a ratchet wheel (94) which is driven in turn by an actuator pawl (80), actuated by movement of a canister (20); two-step ribs (144, 146) being provided to prevent rocking of the canister (20); a drain hole (194) being provided for preventing misting of a display window (118); and frictional surfaces (132, 134) being provided on a shaft (108) of a tape stock bobbin (110) to prevent tape slippage; a rotation regulator being provided for the stock bobbin and comprising a wavelike engagement surface (300) with concavities (302) which engage against control elements (128, 130) in the form of protrusions on resilient forks of a split pin (108) thereby permitting incremental unwinding of the stock bobbin yet resisting excessive rotation if the inhaler is dropped onto a hard surface.

    摘要翻译： 手动操作的测量剂量吸入器（12）包括剂量计数器室（66），其包括由棘轮（94）驱动的剂量显示带（112），所述剂量显示带由致动器棘爪（80）依次驱动， 罐（20）; 提供两级肋（144,146）以防止罐（20）摇动; 设置用于防止显示窗（118）雾化的排水孔（194）; 并且摩擦表面（132,134）设置在带状线轴（110）的轴（108）上，以防止胶带滑动; 旋转调节器被设置用于股票线轴并且包括具有凹陷（302）的波纹接合表面（300），所述波形接合表面（300）与分裂销（108）的弹性叉上的突起形式的控制元件（128,130）接合，从而允许 如果吸入器落在硬表面上，则库存筒管的增量展开能抵抗过度旋转。