专利检索 ap:("Université Montpellier 2, Sciences et Techniques" OR "Institut Curie" OR "INSERM (Institut National de la Santé et de la Recherche Scientifique)" OR "Centre Hospitalier Universitaire de Montpellier" OR "Centre National de la Recherche Scientifique" OR "Université Montpellier I") AND inv:"JOUBERT, Dominique" 第 3 页

21.

发明公开
PROGASTRIN INHIBITORS IN THE TREATMENT OF COLON CANCER 审中-公开
标题翻译：前胃泌素抑制剂用于结肠癌的治疗

公开(公告)号：EP2040753A2

公开(公告)日：2009-04-01

申请号：EP07734620.3

申请日：2007-05-21

申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , Université de Montpellier I

发明人： HOLLANDE, Frédéric , JOUBERT, Dominique , JAY, Philippe , PANNEQUIN, Julie , DELAUNAY, Nathalie , BOURGAUX, Jean-François

IPC分类号： A61K45/00 , A61K39/00

CPC分类号： C07K16/26 , C07K2317/34 , C07K2317/76 , C12N15/1135 , C12N15/1136 , C12N2310/111 , C12N2310/14

摘要： The present invention relates to inhibitors of progastrin induced repression of ICAT for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/Tcf-4-mediated transcriptional pathway is constitutively active.