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公开(公告)号:EP4047348A1
公开(公告)日:2022-08-24
申请号:EP22155350.6
申请日:2022-02-07
Applicant: SYSMEX CORPORATION
Inventor: Shida, Yuki , Komaki, Takanori , Yokoyama, Daisuke , Abe, Masaki
IPC: G01N15/14
Abstract: Disclosed is a hemolytic reagent comprising a nonionic surfactant represented by formula (I) below:
R 1 -R 2 -(CH 2 CH 2 O) n -H Formula (I)
where Ri represents an alkyl group, an alkenyl group, or an alkynyl group having 8 or more and 25 or less carbon atoms,
R 2 represents an oxygen atom, (COO) or a group represented by formula (II) below:
where n is 23 or larger and 25 or smaller, or 30,
with n of 23 or larger and 25 or smaller, a concentration of the nonionic surfactant is 1700 ppm or higher and 2300 ppm or lower, and
with n of 30, the concentration of the nonionic surfactant is 1900 ppm or higher and 2300 ppm or lower.-
公开(公告)号:EP3964838A3
公开(公告)日:2022-07-27
申请号:EP21192344.6
申请日:2021-08-20
Applicant: SYSMEX CORPORATION
Inventor: Kato, Akihito , Kurono, Hiroshi
Abstract: Disclosed is a calibration curve setting method for setting a calibration curve, the calibration curve setting method including: creating a first calibration curve on the basis of a measurement value obtained by measuring a standard sample for which a concentration of a predetermined component is known; creating a second calibration curve by correcting the created first calibration curve; displaying a screen configured to support an operator for restoring the second calibration curve to the first calibration curve; receiving an instruction of restoring the second calibration curve to the first calibration curve; and displaying the first calibration curve upon receiving the instruction of restoring.
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公开(公告)号:EP4027130A1
公开(公告)日:2022-07-13
申请号:EP22158870.0
申请日:2008-01-30
Applicant: SYSMEX CORPORATION
Inventor: Nagai, Takaaki , Narisada, Noriyuki , Fukuma, Daigo , Imazu, Masanori
Abstract: A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.
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公开(公告)号:EP3967328A1
公开(公告)日:2022-03-16
申请号:EP20782720.5
申请日:2020-03-27
Applicant: SYSMEX CORPORATION
Inventor: BAN, Ikuya , YOSHIKAWA, Haruhisa , ORITA, Ayako , IMANISHI, Takeshi
IPC: A61K48/00 , A61P31/00 , A61P31/12 , A61P35/00 , C07H19/067 , C07H19/167 , C07H21/02 , C12N15/11 , C12N15/113 , C12Q1/6844 , C12Q1/6876 , A61K31/7088
Abstract: The present invention addresses the problem of providing a novel artificial nucleic acid, a method for producing the artificial nucleic acid, and a use of the artificial nucleic acid. The problem can be solved by an artificial nucleic acid having a unit derived from a compound represented by formula (1) or a salt thereof:
(wherein "Base" represents an aromatic heterocyclic group which may have a substituent, or an aromatic hydrocarbon ring group which may have a substituent; A 1 represents a linear alkylene group; A 2 represents a single bond or an alkylene group; X represents an alkylene group which may have a substituent; R 1 and R 2 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, a cycloalkyl group which may have a substituent, a cycloalkenyl group which may have a substituent, an aryl group which may have a substituent, a protecting group for a hydroxyl group, a phosphino group which has a substituent, a dihydroxyphosphinyl group which may have a substituent, or a hydroxymercaptophosphinyl group which may have a substituent, or R 1 , R 2 , two oxygen atoms respectively adjacent to R 1 and R 2 and carbon atoms at position-3 and position-5 in a furanose together form a ring which may have a substituent; and R 3 represents an amino group which may have a substituent).-
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公开(公告)号:EP3916012A3
公开(公告)日:2022-02-23
申请号:EP21176405.5
申请日:2021-05-28
Applicant: SYSMEX CORPORATION
Inventor: ABO, Hirotaka , IDE, Nobuyuki
Abstract: Disclosed is a method for producing an alkaline phosphatase fusion antibody, comprising: culturing a cell comprising an expression vector comprising a gene encoding alkaline phosphatase derived from bovine small intestine or Shewanella bacterium and a gene encoding an antibody in a medium comprising a zinc ion, and acquiring an alkaline phosphatase fusion antibody expressed by the cell.
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公开(公告)号:EP3945527A1
公开(公告)日:2022-02-02
申请号:EP21187926.7
申请日:2021-07-27
Applicant: SYSMEX CORPORATION
Inventor: Jimenez, Ariel , Rodgers, Amanda , Diemeke, Robert , Dahlberg, Mark
Abstract: An analyzer analyzes patient samples and the test results are then validated. The validation of test results may be performed either remotely over a network or at a local computer. For example, while network communication errors may prevent remote validation, the local validation could still be performed, which allows auto validation to be continuously performed. The validation of the test results of the patient sample obtained by the analyzer may further be performed by: 1) the first rule included in the first system of the laboratory; and 2) the second rule included in the second system accessible remotely via the network. The present disclosure further relates to an inspection management method based on at least one of the two rules.
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公开(公告)号:EP3933853A1
公开(公告)日:2022-01-05
申请号:EP21181414.0
申请日:2021-06-24
Applicant: SYSMEX CORPORATION
Inventor: Ikeda, Koji , Takahata, Takayuki , Onoe, Hiroko
IPC: G16H80/00
Abstract: Disclosed is a support method for supporting, by using a computer, management of an expert meeting in which a plurality of medical workers interpret a result of a panel test for a patient, and the support method includes: obtaining request information of a plurality of panel tests for patients for each of whom the expert meeting is held; generating information of predicted meeting frames that are related to a number of meetings and/or a meeting time and that are predicted on a scheduled date for holding the expert meeting, based on the obtained request information of the plurality of panel tests; and generating divergence information indicating a difference between the predicted meeting frames and set meeting frames that are related to a number of meetings and/or a meeting time and that are preset on the scheduled date, such that the difference is recognizable.
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公开(公告)号:EP3851190A3
公开(公告)日:2021-10-20
申请号:EP20216907.4
申请日:2020-12-23
Applicant: SYSMEX CORPORATION
Inventor: Tanaka, Hironori , Hamano, Seiji , Kuze, Masato
Abstract: A reagent container is disclosed that is installed in an analyzer and stores a reagent supplied to the analyzer via an aspiration tube. The reagent container 100 includes a container body 10. The container body 10 comprises a tubular member 20 with an opening into which the aspiration tube 90 is inserted from above, and a bag-shaped member 30 joined to the tubular member 20 and storing the reagent. The container body 10 comprises a penetration prevention member for preventing a tip 91 of the aspiration tube 90 inserted through the opening from penetrating the container body10.
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公开(公告)号:EP3854808A1
公开(公告)日:2021-07-28
申请号:EP21152856.7
申请日:2021-01-22
Applicant: SYSMEX CORPORATION
Inventor: MAETA, Shingo , FUKUNAGA, Atsushi , BAJAJ, Reema
Abstract: Disclosed is a method for improving affinity of an antibody for an antigen, comprising, in an unmodified antibody, improving affinity for an antigen as compared to the unmodified antibody, by changing 77th, 79th and 81st amino acid residues of a light chain defined by Kabat method to charged amino acid residues.
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公开(公告)号:EP3799054A1
公开(公告)日:2021-03-31
申请号:EP20197191.8
申请日:2020-09-21
Applicant: SYSMEX CORPORATION
Inventor: Takahata, Takayuki , Ikeda, Koji , Suzuki, Kenichiro , Onoe, Hiroko
Abstract: Disclosed is a method for managing a test request for gene panel testing by a computer, the method including: acquiring, for each of a plurality of test requests, information regarding the test request and an attribute of a test result in the gene panel testing; and outputting display information for displaying a plurality of the test requests and the attribute in association with each other.
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