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54 条记录 (耗时 0.018 秒)

    NOVEL ANTI-PD-1 ANTIBODIES
    33.
    发明公开
    NOVEL ANTI-PD-1 ANTIBODIES 审中-公开

    公开(公告)号：EP4458417A2

    公开(公告)日：2024-11-06

    申请号：EP24191585.9

    申请日：2016-08-11

    申请人： Wuxi Biologics Ireland Limited

    发明人： ZHENG, Yong ,  LI, Jing ,  CHEN, Zhisheng

    IPC分类号： A61P35/00

    摘要： The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.

    INTELLIGENT GENE SYNTHESIS AND MONOCLONAL SELECTION SYSTEM
    34.
    发明公开
    INTELLIGENT GENE SYNTHESIS AND MONOCLONAL SELECTION SYSTEM 审中-实审

    公开(公告)号：EP4431590A1

    公开(公告)日：2024-09-18

    申请号：EP22892104.5

    申请日：2022-11-11

    申请人： Innovel Intelligent Technology Co., Ltd. ,  WuXi Biologics Ireland Limited

    发明人： CHEN, Hao ,  YANG, Kailin ,  ZHI, Yan ,  CHEN, Xiaoyue

    IPC分类号： C12M1/00 ,  C12M1/34 ,  G01N35/00

    CPC分类号： G01N35/00 ,  C12M1/34 ,  C12M1/00

    摘要： An intelligent system for gene synthesis and monoclonal picking, comprising: a core operation module for performing operations associated with gene synthesis and monoclonal picking; and a control system for controlling at least a part of operations of corresponding compartments of the core operation module. The core operation module at least includes: a liquid operation compartment for performing operations of mixing gene fragments and mixing synthetizing reagents with biological samples in the process of gene synthesis; a purification compartment for performing purification operations on nucleic acid products created after the mixing; an amplification compartment for performing amplification operations and error correction operations on fragments of the nucleic acid products and performing culturing and amplification operations on vectors; and a monoclonal picking compartment for performing monoclonal picking operations on purified and cultured nucleic acid products.