摘要:
Disclosed is an apparatus for deploying a bronchial isolation device (115) in a bronchial passageway in a lung of a patient. In one embodiment, the apparatus includes an outer shaft (820) having a distal end. A housing (850) is coupled to the distal end of the outer shaft and configured to receive the bronchial device. An inner shaft (825) is slidably disposed within the outer shaft. A handle (1510) is adapted to move the outer shaft relative to both the inner shaft and the handle while the inner shaft remains fixed relative to the handle so as to eject the bronchial isolation device from the housing.
摘要:
An implantable device (10) for providing one-way flow of air through a lumen in a human lung to reduce the volume of air trapped in a diseased portion of the lung by occluding the lumen to prevent inhalation while permitting expiration out of the diseased portion. The implantable device (10) is deployable in the lumen with a catheter. The device (10) comprises an umbrella-shaped, one-way valve (14). The valve (14) is collapsible for containment within a catheter and expandable in situ when deployed to occlude the lumen. The valve (14) defines a longitudinal axis and comprises a plurality of metal struts (30), a resilient membrane (32), and a central post (34). The device (10) further comprises an anchor (12) for securing the implantable device (10) within the lumen. The anchor (12) comprises a tapered distal end (24) for penetrating the wall of the lumen, and a planar member (26) positioned to limit advancement of the anchor (12) into the lumen. The implantable device (10) further comprises a mechanism (16) connecting the one-way valve (14) to the anchor (12). The mechanism (16) is disposed along the longitudinal axis when the device (10) is collapsed. The mechanism (16) is configured to permit the valve (14) to be oriented at an angle to said anchor (12) when deployed. Accordingly, the anchor (12) can be positioned in a section of the lumen that is at an angle to a section of said lumen in which said one-way valve (14) is positioned.
摘要:
An intra-bronchial device (100) may be placed and anchored in an air passageway (50) of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member (110) that prevents air from being inhaled into the lung portion, and an anchor (112) that anchors the obstruction device (110) within the air passageway. The anchor (112) may piercingly engage the air passageway wall. The anchor (112) may be releasable from the air passageway wall. The anchor (112) may be releasable from the air passageway for removal of the obstructing member (110). The anchor (112) may be releasable by collapsing a portion of the obstructing member (110), or by drawing the obstructing member toward the larynx. The obstructing member (110) may be a one-way valve.
摘要:
Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.
摘要:
A stent delivery system (10) for positioning a stent (18) in a body lumen and an endoscope (20) adapted to position in the stent delivery system for facilitating direct visual observation during placement of the stent. The stent delivery system includes a first conduit (12) wherein the endoscope is positionable, a second conduit (14), wherein the first conduit is positionable, function to releasably position the stent in the body lumen during use. The stent delivery system also includes a lock (16) that functions to inhibit movement of the first conduit relative to the second conduit during use. Retraction of the distal end of the second conduit, relative to the first conduit and the stern, deploy the stent in a body lumen. Indicia (36), visibly positioned on the proximal end of the stent delivery system, function to facilitate determination of an extent of deployment of the stent during use.
摘要:
Disclosed is a flow control device (610) for a bronchial passageway (15). The device can include a valve member (620) that regulates fluid flow through the flow control device (610), a frame (615) coupled to the valve member (620), and a membrane (625) attached to the frame. At least a portion of the flow control device (610) forms a seal with the interior wall of the bronchial passageway (15) when the flow control device (610) is implanted in the bronchial passageway (15). The membrane (625) forms a fluid pathway from the seal into the valve member (620) to direct fluid flowing through the bronchial passageway (15) into the valve member (610).
摘要:
Disclosed are methods and devices for treating the lung. A guidewire exchange technique and device can be used to deliver a guidewire to a lung using a delivery device and a grasping tool that couples the guidewire to the delivery device. A bronchial isolation device can be deployed within a bronchial passageway and removed therefrom using the removal methods and devices described herein. A flow control device can be implanted into a channel in a wall of a bronchial passageway to modify the flow dynamic to and from a target lung region.
摘要:
The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. The device includes a flow control member (90) for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member (90) from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member (90). The control member (90) may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member (90) may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member (90) may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.
摘要:
An intra-bronchial device may be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member (40) that prevents air from being inhaled into the lung portion to collapse the lung portion, and an anchoring device (100) that anchors the obstructing member in the air passageway by engaging the obstructing member (90) and the air passageway wall. The anchoring device (100) may frictionally engage the obstructing member and the air passageway, or engage both by piercing. The engagement provided by the anchoring device may be releasable for removal of the obstructing member (90). The anchoring device (100) may be balloon expandable from a first shape to a second shape that engages the obstructing member (90) and the air passageway. The obstructing member (90) may be a one-way valve.
摘要:
Devices and related methods are directed to altering gaseous flow within a lung to improve the expiration cycle of, for instance, an individual having Chronic Obstructive Pulmonary Disease. More particularly, conduits maintain collateral openings or channels through the airway wall so that air is able to pass directly out of the lung tissue to facilitate both the exchange of oxygen ultimately into the blood and/or to decompress hyper-inflated lungs. The conduits include a center section with a passageway extending through the center section. The conduits further include a distal cage structure which has a passageway and at least one opening in fluid communication with the center section passageway. The medical kits disclosed herein are also directed to maintain collateral openings through airway walls.