摘要:
An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a second portion at the distal end and at least one lumen associated with at least one of the first structural arrangement and/or the second structural arrangement. The first structural arrangement and/or the second structural arrangement can be configured to position the at least one lumen at a particular position with respect to the tissue. A tip is configured to aid in the insertion of the apparatus into the tissue(s).
摘要:
Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.
摘要:
Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assembly comprises first and second inflatable ovoids and an ovoid support mechanism. The first and second inflatable ovoids are adapted for insertion within fornices of a patient. First and second retractors are adapted to be coupled to the ovoid assembly. The first retractor is adapted to be positioned to retract the bladder of a patient during treatment. The second retractor is adapted to be positioned to retract the rectum of a patient during treatment. The tandem and the first and second inflatable ovoids are adapted to be coupled to a radioactive source to deliver an implant radiation dose suitable for cancer treatment at a cancerous cervical treatment site in a patient.
摘要:
There is provided a transendoscopic medical instrument which can insert, remove and latch a plurality of medical items including a flexible guide unit with respect to a transendoscopic sheath which is selectively inserted into a body cavity such as a bronchial branch.
摘要:
Method and apparatus (20) employing ionizing radiation for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus (20) may include a catheter (20) in which a radiation source (42) is advanced hydraulically after the catheter (20) is in place within the heart. Various fixation devices (72) are also disclosed for fixing the location of the catheter (20) within the heart.
摘要:
An afterloader for safely and rapidly advancing a flexible ribbon with a radioactive source (42) through a lumen of a catheter within a patient includes a containment vessel (12), a ribbon extension stop, a ribbon retraction stop, emergency ribbon retraction, ribbon drive mechanism, slip clutch (18), ribbon position indicator (30), security lock mechanism (32), ribbon brake (22), and other novel features.
摘要:
Devices and methods for rendering an intravascular device such as a stent radioactive in-situ, after placement. A device is provided having a surface (20) and a first substance (22) immobilized thereon. The first substance (22) preferably has a high and selective affinity for a second substance (26) which can be radioactive, cytotoxic or thrombolytic. The first substance (22) can also have an affinity for growth factors or thrombolytic, chemolytic or cytotoxic agents. The device can be placed across a stenosed blood vessel region, preferably after dilation by angioplasty or atherectomy. After device placement within the vessel, the second substance (26) can be injected into the blood stream of a patient. With each pass through the device, the second substance (26) is increasingly bound to the first substance (22) on the device surface (20). Suitable complementary substance pairs include avidin and radio-labeled biotin, protamine and radioactive heparin, and protein and anti-protein antibody.