公开(公告)号：EP3256571A1

公开(公告)日：2017-12-20

申请号：EP16749976.3

申请日：2016-02-12

申请人： Takeda Vaccines, Inc.

发明人： RAO, Raman

IPC分类号： C12N7/00

CPC分类号： C12N7/00 ,  A61K39/125 ,  A61K2039/5252 ,  C12N2770/32334 ,  C12N2770/32351 ,  C12N2770/32363

摘要： The present disclosure relates to methods of producing Enterovirus A, e.g., for vaccine production, that include culturing cells in a fixed bed bioreactor. Further provided herein is an Enterovirus A produced by the methods of production disclosed herein, as well as compositions, immunogenic compositions, and vaccines related thereto.

公开(公告)号：EP2731621B1

公开(公告)日：2017-11-01

申请号：EP12811916.1

申请日：2012-07-11

申请人： Takeda Vaccines, Inc.

发明人： RICHARDSON, Charles ,  BARGATZE, Robert, F. ,  MENDELMAN, Paul, M.

IPC分类号： A61K39/125

CPC分类号： A61K39/12 ,  A61K39/125 ,  A61K39/39 ,  A61K2039/5258 ,  A61K2039/545 ,  A61K2039/55505 ,  A61K2039/55572 ,  A61K2039/70 ,  C12N2770/16034

公开(公告)号：EP3052631A4

公开(公告)日：2017-06-14

申请号：EP14850556

申请日：2014-10-03

申请人： TAKEDA VACCINES INC

发明人： HAYNES JOEL

IPC分类号： C12N7/00

CPC分类号： C07K14/005 ,  A61K39/205 ,  A61K2039/5258 ,  C07K1/14 ,  C12N7/00 ,  C12N2760/20021 ,  C12N2760/20023 ,  C12N2760/20034 ,  C12N2760/20051 ,  C12N2760/20052 ,  C12N2770/16023 ,  C12Q1/701 ,  C12Q2600/158

摘要： The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free of a virus. The disclosure also relates to compositions, methods, assays, and kits for detecting a rhabdovirus in a sample.

摘要翻译： 本公开涉及用于检测昆虫细胞中产生的产物中病毒的存在和去除病毒的组合物，方法，混合物和试剂盒。 本公开还涉及在昆虫细胞中产生并且不含或基本上不含病毒的蛋白质，肽，多肽，药物物质，生物制品，疫苗抗原和病毒样颗粒。 本公开还涉及用于检测样品中弹状病毒的组合物，方法，测定法和试剂盒。