Abstract:
Embodiments as disclosed herein may provide a sensor system including a container, such as a bag, having a port assembly integrated therewith. The port assembly includes an optically transparent window and be configured such that a sensor may be mechanically attached to the port assembly to interface with the optical window. The sensor may include an index of refraction (IoR) sensor that measures the chemical concentration of a liquid inside the container based on a refractive index.
Abstract:
One example discloses an interferometer device (100), including: a first side (102), having a first reflectivity (104); a second side (106), having a second reflectivity (108); a cavity (110) disposed between the first and second sides, and having an opening (112) configured to receive a substance (114), such as carbon dioxide; an electromagnetic source input region (116) configured to receive an electromagnetic signal(118); and an electromagnetic detector output region (122) configured to output the electromagnetic signal (124) modulated in response to the substance in the cavity. Another example discloses a method including: fabricating a first side, having a first reflectivity; fabricating a second side, having a second reflectivity and positioned with respect to the first side so as to form a cavity; fabricating an opening configured to receive a substance; fabricating an electromagnetic source input region configured to receive an electromagnetic signal; and fabricating an electromagnetic detector output region configured to output the electromagnetic signal modulated in response to the substance in the cavity. Preferably, the first side, the second side and the cavity form a Fabry-Perot etalon.
Abstract:
The present invention relates to a micromechanical photothermal analyser of microfluidic samples comprising an oblong micro-channel extending longitudinally from a support element, the micro-channel is made from at least two materials with different thermal expansion coefficients, wherein the materials are arranged relatively to each other so that heating of the micro-channel results in a bending of the micro-channel, the first material has a first thermal expansion coefficient and is made from an light-specific transparent penetrable material so that when exposed to ultraviolet, visible, or infrared light, the specific light radiates into the channel through said light transparent material, the second material has a second thermal expansion coefficient being different from the first thermal expansion coefficient. The micromechanical photothermal analyser also comprises an irradiation source being adapted to controlled radiate ultraviolet, visible, or infrared light towards and through the transparent micro-channel, and a deflection detector being adapted to detect the amount of deflection of the micro-channel. The wavelength-deflection plot provides a spectrum of an analyte inside the oblong microchannel. To characterize the analyte the plot is compared with the standard database of spectroscopy.
Abstract:
An automatic analyzer including: a multi-wavelength light source 44 that irradiates with multi-wavelength light a reaction cuvette 2 containing a liquid mixture of a sample to be analyzed and a reagent; a transmitted-light quantity detector 45 that detects the amount of light transmitted through the reaction cuvette 2 and internal contents of the reaction cuvette; a single-wavelength light source 14 that irradiates the reaction cuvette 2 with single-wavelength light; a transmitted-light quantity detector 15 that detects the amount of single-wavelength light scattered from the reaction cuvette 2 and the internal contents of the reaction cuvette; and a memory 11 for storing a result of the transmitted-light quantity detection with the transmitted-light quantity detector 45 and a result of the scattered-light quantity detection with the scattered-light quantity detector 15; wherein deterioration states of the single-wavelength light source 14, multi-wavelength light source 15, and reaction cuvette 2 are determined in accordance with measurement results of cell blank measurements conducted on the reaction cuvette where a predetermined reference solution is stored to detect the amount of light transmitted through and the amount of light scattered from. A decrease in analytical accuracy can be thereby suppressed.
Abstract:
A flow cell for differential refractive index detection. The flow cell includes a transparent body that extends from a first end to a second end along a longitudinal axis. The transparent body defines a sample prism chamber and reference prism chamber. The sample prism chamber is configured to allow fluid flow between the first and second ends of the transparent body along the longitudinal axis. The reference prism chamber is configured to receive a reference fluid. The sample and reference prism chambers each include a grating comprising a plurality of grooves extending along the longitudinal axis in the direction of fluid flow.
Abstract:
Provided is a reagent accommodating/measuring cartridge for mixing and reacting a test specimen with a reagent and for measuring the reaction state thereof with the transmitted light, the cartridge comprising a plurality of transmitted-light measurement chambers having different optical path lengths.
Abstract:
The present invention relates generally to vessels for optical measurements and to a method for using and manufacturing such vessels. More specifically the invention relates to vessels utilized in optical measurements such as fluorescence-based polymerase chain reaction (PCR) methods. The vessel according to the invention comprises an opening and a reduced volume region which is arranged in such a way that during measurement a sample is contained therein or at least moved thereto.
Abstract:
A method for detecting and counting particles suspended in fluids, such as bacteria suspended in urine, utilizing dynamic features of the suspended particles and employing light scattering measurements. The disclosed method is suitable for determining the susceptibility of bacteria to antibiotics. A cuvette for detecting bacteria in fluids, which is especially suited for the light scattering measurements, is provided.