公开(公告)号：EP0700290B1

公开(公告)日：1999-08-25

申请号：EP94918355.2

申请日：1994-05-24

申请人： LABORATOIRE GLAXO WELLCOME (S.A.)

发明人： THIELEMANS, Isabelle ,  RICHARD, Isabelle

IPC分类号： A61K31/415 ,  A61K9/02

CPC分类号： A61K9/02 ,  A61K31/415

摘要： The invention relates to a pharmaceutical composition for rectal administration which comprises 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)-methyl]-4H-carbazol-4-one in the form of its free base or a pharmaceutically acceptable solvate thereof as active ingredient, together with one or more pharmaceutically acceptable carriers or excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine at 5-HT3 receptors are also described.