TRANSFORMANT FOR PRODUCING LACTIC ACID HAVING HIGH OPTICAL PURITY, AND METHOD FOR PRODUCING LACTIC ACID USING SAME
    6.
    发明公开
    TRANSFORMANT FOR PRODUCING LACTIC ACID HAVING HIGH OPTICAL PURITY, AND METHOD FOR PRODUCING LACTIC ACID USING SAME 有权
    转化用于生产乳酸高光学纯度和方法对牛奶酸生产订单

    公开(公告)号:EP2679668A1

    公开(公告)日:2014-01-01

    申请号:EP11859480.3

    申请日:2011-02-23

    申请人: Macrogen Inc.

    IPC分类号: C12N1/21 C12N15/53 C12P7/56

    摘要: Disclosed is the biological production of lactic acid using a microorganism. A transformant capable of producing lactic acid of high optical purity at high yield, a method for the preparation thereof, and a method for producing lactic acid in a convenient and economically beneficial manner using the same are provided. The Zymomonas mobilis transformant can produce lactic acid of high optical purity at high yield without a stringent limitation to production conditions and a regulation of the intracellular metabolism pathway. Because it requires no additional separation and purification steps, the use of the transformant allows the production of lactic acid in a short process, resulting in a significant reduction in production cost, and avoiding the environment problems caused by precipitate wastes, which brings about environmental issues.

    摘要翻译: 公开的是使用微生物的乳酸的生物生产。 能够以高产率制备高光学纯度的乳酸的一种转化体,提供了用于其制备,以及使用相同的便利和经济上有利的方式生产乳酸的方法的方法。 的运动发酵单胞转化体可产生高收率的高光学纯度的乳酸没有严格限制生产条件和细胞内代谢途径的调节。 因为它不需要额外的分离和纯化步骤,利用转化的允许生产乳酸在很短的过程,导致生产成本显著降低,避免了沉淀废物造成的环境问题,这带来的环境问题 ,

    Diagnosis of HER-2 positive breast cancer
    8.
    发明公开
    Diagnosis of HER-2 positive breast cancer 有权
    诊断疱疹HER2阳性Brustkrebs

    公开(公告)号:EP2228455A1

    公开(公告)日:2010-09-15

    申请号:EP10155167.9

    申请日:2010-03-02

    申请人: Macrogen Inc.

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6886 C12Q2600/156

    摘要: A diagnostic technology for breast cancer, in particular, caused by Her-2 copy number variation is provided. Said diagnostic technology identifies the amplification attributable to Her-2 copy number variations and thus allows correct, convenient and rapid diagnosis of breast cancer caused by the amplification attributable to Her-2 copy number variations. As such, said diagnostic technology is highly beneficial for customized treatments of breast cancer such as the therapy using Her-2 antibody (e.g. Herceptin).

    摘要翻译: 提供了一种乳腺癌诊断技术,特别是由Her-2拷贝数变异引起的。 所述诊断技术鉴定归因于Her-2拷贝数变异的扩增,从而允许由归因于Her-2拷贝数变异引起的扩增引起的乳腺癌的正确,方便和快速诊断。 因此,所述诊断技术对于乳腺癌的定制治疗(例如使用Her-2抗体(例如赫赛汀)的治疗))是非常有益的。