公开(公告)号：EP3394095B1

公开(公告)日：2023-09-27

申请号：EP16880019.1

申请日：2016-12-21

发明人： QUINONES-GARCIA, Igor ,  GUEY, Lin ,  LOWE, Kris ,  NGUYEN, Vinh ,  HE, Bing ,  BANDEKAR, Amey ,  BASU, Sujit

IPC分类号： C07K14/78 ,  A61K38/39 ,  A61K8/65 ,  A61K8/60 ,  A61Q19/08

公开(公告)号：EP2917730B1

公开(公告)日：2018-09-12

申请号：EP13853466.4

申请日：2013-11-07

申请人： Phoenix Tissue Repair, Inc.

发明人： MAGIL, Sheila, G.

IPC分类号： G01N33/53 ,  G01N33/68

CPC分类号： G01N33/94 ,  G01N33/6887 ,  G01N2333/78

摘要： The present disclosure features a method of detecting and/or quantifying collagen VII or a fragment thereof in a sample, the method including contacting the sample with collagen IV or a fragment thereof which binds to collagen VII; and contacting the sample with an anti-collagen VII antibody, wherein the anti-collagen VII antibody binds to the NC2 domain of collagen VII; detecting binding of the anti-collagen VII antibody to thereby detect and/or quantify an amount of collagen VII or the fragment thereof in the sample. A method of evaluating or processing a collagen VII preparation is also provided.

公开(公告)号：EP3394095A1

公开(公告)日：2018-10-31

申请号：EP16880019.1

申请日：2016-12-21

申请人： Phoenix Tissue Repair Inc.

发明人： QUINONES-GARCIA, Igor ,  GUEY, Lin ,  LOWE, Kris ,  NGUYEN, Vinh ,  HE, Bing ,  BANDEKAR, Amey ,  BASU, Sujit

IPC分类号： C07K14/78 ,  A61K38/39 ,  A61K8/65 ,  A61K8/60 ,  A61Q19/08

CPC分类号： A61K8/60 ,  A61K8/20 ,  A61K8/24 ,  A61K8/44 ,  A61K8/4993 ,  A61K8/65 ,  A61K38/39 ,  A61Q19/08 ,  C07K14/78

摘要： The present disclosure relates to compositions comprising collagen 7 and methods of using the same to treat DEB.

公开(公告)号：EP3429615A1

公开(公告)日：2019-01-23

申请号：EP17767212.8

申请日：2017-03-10

申请人： Phoenix Tissue Repair, Inc.

发明人： QUINONES-GARCIA, lgor ,  SIMEONE, Benjamin ,  LILLIE, Raymond ,  YANG, Ting ,  NICHOLS, David

IPC分类号： A61K38/39 ,  C07K1/14 ,  C07K1/16 ,  C07K1/34 ,  C07K14/78

公开(公告)号：EP3418740A1

公开(公告)日：2018-12-26

申请号：EP18186894.4

申请日：2013-11-07

申请人： Phoenix Tissue Repair, Inc.

发明人： MAGIL, Sheila, G

IPC分类号： G01N33/53 ,  G01N33/68

CPC分类号： G01N33/94 ,  G01N33/6887 ,  G01N2333/78

摘要： The invention features a method of detecting and/or quantifying collagen VII by contacting the sample with collagen IV which binds to collagen VII; and detecting binding of collagen IV with collagen VII. Collagen VII is a major component of anchoring fibrils, which help anchor the top layer of the skin, the epidermis, to the underlying dermis, and thus strengthen and stabilize the skin.

公开(公告)号：EP4415745A1

公开(公告)日：2024-08-21

申请号：EP22802427.9

申请日：2022-10-12

申请人： Phoenix Tissue Repair, Inc.

发明人： LANDY, Hal ,  RAVINDRAN, Sanuj

IPC分类号： A61K38/39 ,  A61P17/02 ,  C07K14/78

CPC分类号： A61K38/39 ,  C07K14/78 ,  A61P17/02