摘要:
Compositions and methods for treating contaminated soil and/or ground water in situ. The compositions and methods comprise stabilized forms of colloidal activated carbon that are used to quickly sorb contaminants. Unlike traditional activated carbon in granular or powder form, the compounds and methods of the present invention are operative to transport particulate activated carbon through a matrix of soil and groundwater upon application by injection, gravity feed, or percolation into soil and groundwater, which in turn decontaminate groundwater in place without the cost or disruption associated with digging the contaminated soil and groundwater out of the ground for on-site purification or disposal at a hazardous waste landfill.
摘要:
Compositions and methods for treating contaminated soil and/or ground water in situ. The compositions and methods comprise stabilized forms of colloidal activated carbon that are used to quickly sorb contaminants. Unlike traditional activated carbon in granular or powder form, the compounds and methods of the present invention are operative to transport particulate activated carbon through a matrix of soil and groundwater upon application by injection, gravity feed, or percolation into soil and groundwater, which in turn decontaminate groundwater in place without the cost or disruption associated with digging the contaminated soil and groundwater out of the ground for on-site purification or disposal at a hazardous waste landfill.
摘要:
A biosensor device for detecting small molecules analytes is provided. The device employs a first class of molecules, e.g., protein that binds to both the analyte and a second class of molecules, e.g., nucleic acid. The binding of the protein to the analyte and nucleic acid can be mutually exclusive, and the presence of analyte in a sample results in a detectable displacement of protein from nucleic acid. Alternatively, binding of the protein to the nucleic acid can depend on the presence of analyte in the sample. In a specific embodiment, either the protein or nucleic acid is immobilized on a solid phase support. An arsenic detection system is exemplified. An ArsR binding sequence from the E. coli ars operon is immobilized on a gold-plated surface. ArsR protein binds to the DNA in the absence of arsenic, and is released in the presence of sodium arsenate or phenylarsine oxide. Protein release results in a change in surface plasmon resonance, and the magnitude or kinetics of the change indicate the concentration of arsenic.
摘要:
Compositions and methods for treating contaminated soil and/or ground water in situ. The compositions and methods comprise stabilized forms of colloidal activated carbon that are used to quickly sorb contaminants. Unlike traditional activated carbon in granular or powder form, the compounds and methods of the present invention are operative to transport particulate activated carbon through a matrix of soil and groundwater upon application by injection, gravity feed, or percolation into soil and groundwater, which in turn decontaminate groundwater in place without the cost or disruption associated with digging the contaminated soil and groundwater out of the ground for on-site purification or disposal at a hazardous waste landfill.
摘要:
The present invention provides for a family of novel compositions to serve as substrates that release hydroxy acid slowly over time. Preferably the hydroxy acid is an α-hydroxy acid, more preferably it is lactic acid. The compositions are preferably made by reaction of poly(lactic acid) with multifunctional alcohols. Also disclosed are formulations based on the compounds and methods of use for both the compositions and the formulations. The preferred use of the compositions and formulations of the present invention is for bioremediation purposes wherein they provide a time-release source of lactic acid to support the growth and reductive activity of microbes present in a system or medium, such as an aquifer, bioreactor, soil, industrial process, wastestream, body of water, river or well. The microbes destroy or inactivate compounds which are capable of being reduced, such as nitrogen-containing organic compounds, oxygen-containing organic compounds, polyaromatic hydrocarbons, and halogen-containing organic compounds.
摘要:
Compositions and methods for in situ ground water remediation. The compositions comprise a colloidal biomatrix comprised of sorbent particles, such as zeolites, organoclays and activated carbon, dispersed in aqueous solution that are injectable into the permeable zones of an aquifer to be treated. Once deposited into the permeable zones of the aquifer, the groundwater concentrations of contaminants in those zones are depleted, thus increasing the rate of diffusion of contaminants of the less permeable zones. The compositions and methods of the present invention can be used to treat any organic contaminants and provide rapid remediation of contaminated ground water by adsorption and biodegradation of such contaminants.
摘要:
A biosensor device for detecting small molecules analytes is provided. The device employs a first class of molecules, e.g., protein that binds to both the analyte and a second class of molecules, e.g., nucleic acid. The binding of the protein to the analyte and nucleic acid can be mutually exclusive, and the presence of analyte in a sample results in a detectable displacement of protein from nucleic acid. Alternatively, binding of the protein to the nucleic acid can depend on the presence of analyte in the sample. In a specific embodiment, either the protein or nucleic acid is immobilized on a solid phase support. An arsenic detection system is exemplified. An ArsR binding sequence from the E. coli ars operon is immobilized on a gold-plated surface. ArsR protein binds to the DNA in the absence of arsenic, and is released in the presence of sodium arsenate or phenylarsine oxide. Protein release results in a change in surface plasmon resonance, and the magnitude or kinetics of the change indicate the concentration of arsenic.