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公开(公告)号：EP2986308B1
公开(公告)日：2019-10-16
申请号：EP14872684.7
申请日：2014-12-18
发明人： CHAWLA, Lakhmir
IPC分类号： A61K38/08 , A61K9/00 , A61K31/135 , A61K31/137 , A61P9/02
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公开(公告)号：EP3600295A1
公开(公告)日：2020-02-05
申请号：EP18776871.8
申请日：2018-03-29
申请人： The George Washington University, A Congressionally Chartered Not-For-Profit Corporation , The Board of Trustees of the University of Illinois
IPC分类号： A61K31/42 , A61K31/422 , A61K45/06
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公开(公告)号：EP3607962A1
公开(公告)日：2020-02-12
申请号：EP19197866.7
申请日：2014-12-18
发明人： Chawla, Lakhmir
IPC分类号： A61K38/08 , A61K31/137 , A61P9/02
摘要： The present invention relates, inter alia, to a method comprising administering to a subject having high output shock and undergoing treatment with a catecholamine at a dose equivalent to at least about 0.2 mcg/kg/min of norepinephrine a dose of angiotensin II which is effective to raise the blood pressure of the subject to a mean arterial pressure (MAP) of about 65 mm Hg or above, and which is effective to reduce the dose of the catecholamine required to maintain a MAP of about 65 mm Hg to the equivalent of about 0.05-0.2 mcg/kg/min norepinephrine or less, or to the equivalent of about 0.05 mcg/kg/min norepinephrine or less.
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公开(公告)号：EP3502271A3
公开(公告)日：2019-08-14
申请号：EP19153228.2
申请日：2015-10-22
申请人： The George Washington University, A Congressionally Chartered Not-For-Profit Corporation , Astute Medical, Inc.
摘要： The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising performing one or more assays configured to detect one or more biomarkers on a body fluid sample obtained from the subject to provide one or more assay result(s) and correlating the assay result(s) to the occurrence or nonoccurrence of appendicitis in the subject or likelihood of the future outcome to the subject.
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公开(公告)号：EP3502271A2
公开(公告)日：2019-06-26
申请号：EP19153228.2
申请日：2015-10-22
申请人： The George Washington University, A Congressionally Chartered Not-For-Profit Corporation , Astute Medical, Inc.
CPC分类号： C12Q1/6883 , C12Q2600/158 , G01N33/566 , G01N33/6893 , G01N33/84 , G01N2500/04 , G01N2800/06 , G01N2800/56
摘要： The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising performing one or more assays configured to detect one or more biomarkers on a body fluid sample obtained from the subject to provide one or more assay result(s) and correlating the assay result(s) to the occurrence or nonoccurrence of appendicitis in the subject or likelihood of the future outcome to the subject.
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